MAP4K5 Antibodies

AND MAP4K5 ELISA kits, MAP4K5 Proteins

Many biological assays use antibodies to detect MAP4K5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAP4K5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAP4K5 antibodies...

We validate the specificity of these antibodies to MAP4K5 by testing them on tissues known to express MAP4K5 positively and negatively. Browse below to find the MAP4K5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for MAP4K5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the MAP4K5 Western Blot Guide

Designing an IHC experiment for MAP4K5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the MAP4K5 IHC Guide

MAP4K5 Infographic by Boster Bio

All MAP4K5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MAP4K5 Antibody Picoband®

Western blot analysis of MAP4K5 using anti-MAP4K5 antibody (A10186-1)

IHC analysis of MAP4K5 using anti-MAP4K5 antibody (A10186-1)

IF analysis of MAP4K5 using anti-MAP4K5 antibody (A10186-1)

Human

IF, IHC, ICC, WB

$370
Cat # A10186-1
100 μg/vial

Anti-MAP4K5 Antibody Picoband®

Western blot analysis of MAP4K5 using anti-MAP4K5 antibody (A10186-2)

Flow Cytometry analysis of HepG2 cells using anti-MAP4K5 antibody (A10186-2)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A10186-2
100 µg/vial

MAP4K5 (NM_006575) Human Over-expression Lysate

MAP4K5 Human Over-expression Lysates NM_006575

Human

$628
Cat # LS011183
20 µg, 100 µg

MAP4K5 Overview

Facts about Mitogen-activated protein kinase kinase kinase kinase 5.

MAP4K5 3D structure. Source: alphafold

Mitogen-activated protein kinase kinase kinase kinase 5 (MAP4K5)

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Gene Information

Human
Gene Name:	MAP4K5
Uniprot:	Q9Y4K4
Entrez:	11183

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11; EC 2.7.11.1; GCKR; germinal center kinase-related; KHS1; KHSMEKKK 5; Kinase homologous to SPS1/STE20; MAP4K5; MAPK/ERK kinase kinase kinase 5; MAPKKKK5; MEK kinase kinase 5; mitogen-activated protein kinase kinase kinase kinase 5

Molecular Weight

Mass (kDA):
95.024 kDA

Genomic Context


Human

Location:	14q22.1
Sequence:	14; NC_000014.9 (50418475..50561126, complement)

Tissue Specificity

Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.

Subcellular Localizations

Cytoplasm.

Diseases

Cardiac Failure Chronic
Adenocarcinoma
Lung Neoplasms
Non-small Cell Lung Carcinoma
Heart Failure
Colonic Neoplasms
Diabetes Mellitus
Cardiomyopathy, Dilated
Growth Retardation
Diabetes Mellitus, Non-insulin-dependent
Patient Dependence On

Malignant Neoplasms
Oncolysis
Obesity
Neoplasms
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas

Interacting Proteins

CRK
GRB2
NCK1

Pathways

Clathrin-mediated Endocytosis
Cell Cycle
Insulin Secretion
Endocytosis
Secretion

PTMs

Phosphorylation

Ubiquitination

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAP4K5

References

PMID: 9038372 by Tung R.M., et al. A novel human SPS1/STE20 homologue, KHS, activates jun N-terminal kinase.

PMID: 9788432 by Oehrl W., et al. The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins.