Helicase MOV-10 Antibodies

AND MOV10 ELISA kits, Helicase MOV-10 Proteins

Many biological assays use antibodies to detect Helicase MOV-10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Helicase MOV-10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Helicase MOV-10 antibodies...

We validate the specificity of these antibodies to Helicase MOV-10 by testing them on tissues known to express MOV10 positively and negatively. Browse below to find the MOV10 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MOV10 Infographic by Boster Bio

All MOV10 Products

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Specificity

Applications

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MOV10 (NM_020963) Human Recombinant Protein

$1062
Cat # PROTQ9HCE1
20 µg

Anti-MOV10 Antibody Picoband®

Western blot analysis of MOV10 using anti-MOV10 antibody (A04952)

IHC analysis of MOV10 using anti-MOV10 antibody (A04952)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04952
100 μg/vial

Anti-Mov10 Rabbit Monoclonal Antibody

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature

Western blot analysis of Mov10 expression in (1) 293 cell lysate; (2) NIH/3T3 cell lysate

Human, Mouse, Rat

IHC, WB

$370
Cat # M04952
100 μl/vial

MOV10 (NM_020963) Human Over-expression Lysate

MOV10 Human Over-expression Lysates NM_001130079

Human

$628
Cat # LS004343
20 µg, 100 µg

MOV10 Overview

Facts about Helicase MOV-10.

MOV10 3D structure. Source: alphafold

Helicase MOV-10 (MOV10)

5' to 3' RNA helicase leading to UPF1 mRNA target degradation by translocation along 3' UTRs (PubMed:24726324). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (PubMed:16289642, PubMed:17507929, PubMed:22791714).

In collaboration with FMR1, regulates miRNA- mediated translational repression by AGO2 (PubMed:25464849). Restricts retrotransposition of long interspersed element-1 (LINE- 1) in collaboration with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1 (PubMed:30122351, PubMed:23093941).

Gene Information

Human
Gene Name:	MOV10
Uniprot:	Q9HCE1
Entrez:	4343

Family

Belongs to:

DNA2/NAM7 helicase family

Alternative Names

DKFZp667O1423; EC 3.6.1; EC 3.6.4.13; FLJ32791; KIAA1631mouse) homolog; Mov10, Moloney leukemia virus 10, homolog (mouse)

Molecular Weight

Mass (kDA):
113.671 kDA

Genomic Context


Human

Location:	1p13.2
Sequence:	1; NC_000001.11 (112674312..112702377)

Subcellular Localizations

Cytoplasm, P-body. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm, Stress granule. Nucleus. Cytoplasm. Co-enriched in cytoplasmic foci with TUT4 (PubMed:30122351). In developing neurons, localizes both in nucleus and cytoplasm, but in the adulthood it is only cytoplasmic (By similarity). After infection, relocalizes to the DENV replication complex in perinuclear regions (PubMed:27974568).