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Neurofascin Antibodies

AND NFASC ELISA kits, Neurofascin Proteins

Many biological assays use antibodies to detect Neurofascin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neurofascin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neurofascin antibodies...

We validate the specificity of these antibodies to Neurofascin by testing them on tissues known to express NFASC positively and negatively. Browse below to find the NFASC antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NFASC Infographic by Boster Bio

NFASC protein infographic

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Anti-Neurofascin NFASC Antibody

Western blot analysis of extracts of various cell lines, using NFASC antibody at 1:1000 dilution

Western blot analysis of extracts of various cell lines, using NFASC antibody at 1:1000 dilution

Human, Mouse, Rat

WB

$405
Cat # A04015
100ul

NFASC Overview

Facts about Neurofascin.

NFASC 3D structure

NFASC 3D structure. Source: alphafold

Neurofascin (NFASC)

Cell adhesion, ankyrin-binding protein that might be involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. .

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Gene Information

Human
Gene Name:	NFASC
Uniprot:	O94856
Entrez:	23114

Gene Information

Family

Belongs to:

immunoglobulin superfamily

Family

Alternative Names

DKFZp686P2250; KIAA0756FLJ46866; neurofascin homolog (chicken); neurofascin homolog; Neurofascin; NF; NFASC; NRCAML

Molecular Weight

Mass (kDA):
150.027 kDA

Molecular Weight

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (204828652..205022822)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.; [Isoform 8]: Cell junction, paranodal septate junction.

Subcellular Localization

Diseases

Tissue Adhesions
Nervousness
Sclerosis
Multiple Sclerosis
Demyelination
Demyelinating Diseases
Muscular Fasciculation
Experimental Autoimmune Encephalomyelitis
Ataxia
Neuroblastoma
Nerve Degeneration
Guillain-barre Syndrome
Chimera Disorder

Hypoxia-ischemia, Brain
Lissencephaly
Encephalomyelitis
Autoimmune Reaction
Polyneuropathy
Neuronal Migration Disorders
Trauma, Nervous System

Disease

Pathways

Cell Adhesion
Localization
Myelination
Transport
Neurogenesis
Axon Extension
Cell Proliferation
Receptor Clustering
Regeneration
Rna Interference
Gephyrin Clustering
Cell Migration
Aging

Proteolysis
Clustering Of Voltage-gated Sodium Channels
Schwann Cell Proliferation
Axon Ensheathment
Muscle Attachment
Axon Guidance
Cell-cell Adhesion

Pathways

PTMs

Phosphorylation
Cleavage

Deglycosylation
Glycosylation

Palmitoylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NFASC

References

PMID: 15491607 by Homma K., et al. Alternative splice variants encoding unstable protein domains exist in the human brain.

PMID: 23897819 by Kwon H.S., et al. Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling.