Nuclear factor 1 C-type Antibodies

AND NFIC ELISA kits, Nuclear factor 1 C-type Proteins

Many biological assays use antibodies to detect Nuclear factor 1 C-type, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nuclear factor 1 C-type in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nuclear factor 1 C-type antibodies...

We validate the specificity of these antibodies to Nuclear factor 1 C-type by testing them on tissues known to express NFIC positively and negatively. Browse below to find the NFIC antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Nuclear factor 1 C-type? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NFIC Western Blot Guide

Designing an IHC experiment for Nuclear factor 1 C-type? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the NFIC IHC Guide

NFIC Infographic by Boster Bio

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Anti-NFIC/CTF Antibody Picoband®

IHC analysis of NFIC using anti-NFIC antibody (A04154-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A04154-2
100 μg/vial

NFIC Overview

Facts about Nuclear factor 1 C-type.

NFIC 3D structure. Source: alphafold

Nuclear factor 1 C-type (NFIC)

Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

Gene Information

Human
Gene Name:	NFIC
Uniprot:	P08651
Entrez:	4782

Family

Belongs to:

CTF/NF-I family

Alternative Names

CCAAT-binding transcription factor; CTF5; CTFCCAAT-box-binding transcription factor; MGC20153; NF1-C; NFI; NF-I; NF-I/C; NFI-C; nuclear factor 1 C-type; Nuclear factor 1/C; nuclear factor I/C (CCAAT-binding transcription factor); Nuclear factor I/C; TGGCA-binding protein

Molecular Weight

Mass (kDA):
55.675 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (3359630..3469217)

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Mammary Neoplasms
Neurofibromatosis 1
Liver Carcinoma
Carcinoma
Congenital Absence
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Hydrocephalus
Nervousness
Infective Disorder

Neoplasm Metastasis
Coronary Heart Disease
Asymptomatic Infections
Abscess
Metastatic Malignant Neoplasm To The Lymph Node
Melanoma
Glioma

Pathways

Dna Replication
Root Development
Odontoblast Differentiation
Cell Migration
Cell Proliferation
Rna Splicing
Cell Adhesion
Mammary Gland Involution
Developmental Process
Osteoblast Differentiation
Hypersensitivity
Regulation Of Gene Expression
Ossification

Mesenchymal Cell Proliferation
Viral Transcription
Translation
Axon Guidance
Cell Cycle
Cell Differentiation
Liver Regeneration

PTMs

Reduction
Phosphorylation

Glycosylation
Cleavage

Oxidation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NFIC

References

PMID: 3398920 by Santoro C., et al. A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs.

PMID: 8710515 by Wenzelides S., et al. CTF5 -- a new transcriptional activator of the NFI/CTF family.