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- Table of Contents
Facts about Neurogranin.
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Human | |
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Gene Name: | NRGN |
Uniprot: | Q92686 |
Entrez: | 4900 |
Belongs to: |
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neurogranin family |
calmodulin-binding protein; hng; neurogranin (protein kinase C substrate, RC3); Neurogranin; Ng; NRGN; protein kinase C substrate; RC3; RC3ng
Mass (kDA):
7.618 kDA
Human | |
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Location: | 11q24.2 |
Sequence: | 11; NC_000011.10 (124739942..124747210) |
In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease.
The NRGN is an RNA Gene. It is increasingly used in genetic analysis. The antibody is available in high-affinity versions. This article will help better know the NRGN marker as well as the potential applications. It will also provide FAQs and Pricing information. Interested? Learn more! Below are the most popular uses for the NRGN marker.
Boster bio high-affinity antibody may be used to perform immunohistochemistry using the NRGN marker. This company specializes on the production of picogram-sensitive ELISA kit as well as IHC-optimized polyclonal antibodies. The company's extensive collection of antibodies contains more than 12,000 valid antibodies. These antibodies were evaluated quantitatively against panels comprising 250 mouse and human tissues, untransfected cell lines, and Recombinant proteins.
NRGN is a neuronal proteins with seventy eight amino acids and the 7.6 kDa molecular weight. Its role in synaptic reorganization and cognitive function makes it an attractive candidate for use as a biomarker in the circulating system for acute traumatic brain injury (TBI). Its small dimensions make it an ideal candidate for this test, as it is likely to traverse the blood-brain barrier and thus serve as a useful instrument for diagnosing and treatment of TBI as well as other neurological conditions.
PMID: 8929222 by Mertsalov I.B., et al. Cloning cDNA for human neurogranin.
PMID: 9499372 by Mertsalov I.B., et al. Structure and chromosomal localization of human neurogranin gene.