Neurogranin Antibodies

AND NRGN ELISA kits, Neurogranin Proteins

Many biological assays use antibodies to detect Neurogranin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neurogranin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neurogranin antibodies...

We validate the specificity of these antibodies to Neurogranin by testing them on tissues known to express NRGN positively and negatively. Browse below to find the NRGN antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Neurogranin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the NRGN Western Blot Guide

NRGN Infographic by Boster Bio

All NRGN Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Neurogranin/NRGN Antibody Picoband®

Western blot analysis of Neurogranin/NRGN using anti-Neurogranin/NRGN antibody (A05781-3)

Flow Cytometry analysis of K562 cells using anti-Neurogranin/NRGN antibody (A05781-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A05781-3
100 μg/vial

Neurogranin (NRGN) (NM_006176) Human Over-expression Lysate

Neurogranin (NRGN) Human Over-expression Lysates NM_001126181

Human

$628
Cat # LS004900
20 µg, 100 µg

Human Neurogranin Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ92686
Starting from 10ug

NRGN Overview

Facts about Neurogranin.

NRGN 3D structure. Source: alphafold

Neurogranin (NRGN)

Acts as a"third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic remodeling and development. Binds to calmodulin in the absence of calcium (By similarity).

. .

Gene Information

Human
Gene Name:	NRGN
Uniprot:	Q92686
Entrez:	4900

Family

Belongs to:

neurogranin family

Alternative Names

calmodulin-binding protein; hng; neurogranin (protein kinase C substrate, RC3); Neurogranin; Ng; NRGN; protein kinase C substrate; RC3; RC3ng

Molecular Weight

Mass (kDA):
7.618 kDA

Genomic Context


Human

Location:	11q24.2
Sequence:	11; NC_000011.10 (124739942..124747210)

Tissue Specificity

In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease.

Diseases

Schizophrenia
Hypothyroidism
Depressive Disorder
Vitamin A Deficiency
Nervousness
Alzheimer's Disease
Malnutrition
Neoplasms
Refractory Anemia With Ringed Sideroblasts
Mental Disorders
Impairment (finding)
Impaired Cognition

Spinal Cord Injuries
Pituitary Diseases
Anxiety Disorders
Psychotic Disorders
Congenital Hypothyroidism
Memory Disorders
Memory Impairment

Pathways

Brain Development
Localization
Synaptic Transmission
Aging
Cognition
Transport
Long-term Memory
Lactation
Senescence
Cell Death
Pathogenesis
Protein Phosphorylation
Cellular Homeostasis

Proteolysis
Ribosome Assembly
Cell Cycle Arrest
Membrane Depolarization
Translation
Calcium-mediated Signaling
Cell Cycle

PTMs

Phosphorylation
Oxidation
Carboxylation

Dephosphorylation
Reduction
Ribosylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NRGN

References

PMID: 8929222 by Mertsalov I.B., et al. Cloning cDNA for human neurogranin.

PMID: 9499372 by Mertsalov I.B., et al. Structure and chromosomal localization of human neurogranin gene.