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- Table of Contents
NTSR1 Antibodies
AND NTSR1 ELISA kits, NTSR1 Proteins
Many biological assays use antibodies to detect NTSR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NTSR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NTSR1 antibodies...
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NTSR1 Infographic by Boster Bio
All NTSR1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, WB
$370
Cat # A04610-4
100 μg/vial
Cat # A04610-4
100 μg/vial
Human
$960
Cat # LS004923
20 µg, 100 µg
Cat # LS004923
20 µg, 100 µg
NTSR1 Overview
Facts about Neurotensin receptor type 1.
Neurotensin receptor type 1 (NTSR1)
G-protein coupled receptor for the tridecapeptide neurotensin (NTS) (PubMed:8381365, PubMed:21725197, PubMed:23140271). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system.
Signaling leads to the activation of downstream MAP kinases and protects cells from apoptosis (PubMed:21725197). .
Gene Information
| Human | |
|---|---|
| Gene Name: | NTSR1 |
| Uniprot: | P30989 |
| Entrez: | 4923 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
NTR1; NTRH; NTRR; NTS1; NTSR1
Molecular Weight
Mass (kDA):
46.259 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q13.33 |
| Sequence: | 20; NC_000020.11 (62708770..62762771) |
Tissue Specificity
Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Membrane raft. Palmitoylation is required for localization at CAV1-enriched membrane rafts.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Neoplasm Of Breast
- Neoplasm Invasiveness
- Malignant Paraganglionic Neoplasm
- Cell Invasion
- Neoplasm Metastasis
- Malignant Tumor Of Colon
- Mammary Neoplasms
- Adenocarcinoma
Interacting Proteins
- DRD2
- NTS
Pathways
- Cell Proliferation
- Secretion
- Insulin Secretion
- Fertilization
- Intracellular Signal Transduction
- Behavioral Fear Response
- Energy Homeostasis
- Methylation
- Gastric Emptying
- Feeding Behavior
PTMs
- Demethylation
- Phosphorylation
Research Areas
- GPCR
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NTSR1
bosterbio.com/bosterbio-gene-info-cards/NTSR1
References
PMID: 8381365 by Vita N., et al. Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor.
PMID: 20048080 by Swift S.L., et al. Altered expression of neurotensin receptors is associated with the differentiation state of prostate cancer.