This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
ADP-sugar pyrophosphatase Antibodies
AND NUDT5 ELISA kits, ADP-sugar pyrophosphatase Proteins
Many biological assays use antibodies to detect ADP-sugar pyrophosphatase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADP-sugar pyrophosphatase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADP-sugar pyrophosphatase antibodies...
Designing an IHC experiment for ADP-sugar pyrophosphatase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NUDT5 IHC GuideNUDT5 Infographic by Boster Bio
All NUDT5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A07530
100 µg/vial
Cat # A07530
100 µg/vial
NUDT5 Overview
Facts about ADP-sugar pyrophosphatase.
ADP-sugar pyrophosphatase (NUDT5)
Enzyme that can either act as an ADP-sugar pyrophosphatase in lack of diphosphate or catalyze the synthesis of ATP in existence of diphosphate (PubMed:27257257). In lack of diphosphate, hydrolyzes with similar pursuits various modified nucleoside diphosphates like ADP-ribose, ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP (PubMed:10567213, PubMed:10722730, PubMed:19699693, PubMed:21389046, PubMed:17052728).
Can also hydrolyze additional nucleotide sugars with low activity (PubMed:19699693, PubMed:21389046). In presence of diphosphate, mediates the synthesis of ATP in the nucleus by catalyzing the conversion of ADP-ribose to ATP and ribose 5- phosphate.
Gene Information
| Human | |
|---|---|
| Gene Name: | NUDT5 |
| Uniprot: | Q9UKK9 |
| Entrez: | 11164 |
Family
| Belongs to: |
|---|
| Nudix hydrolase family |
Alternative Names
EC 3.6.1.-; EC 3.6.1.13; hYSAH1; nucleoside diphosphate linked moiety X-type motif 5; Nucleoside diphosphate-linked moiety X motif 5; nudix (nucleoside diphosphate linked moiety X)-type motif 5; Nudix motif 5; NUDT5; YSA1; YSA1H; YSA1HADP-sugar pyrophosphatase
Molecular Weight
Mass (kDA):
24.328 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10p14 |
| Sequence: | 10; NC_000010.11 (12165328..12196144, complement) |
Tissue Specificity
Widely expressed. Most abundant in liver.
Subcellular Localizations
Nucleus.
Diseases
- Growth Retardation
- Retinoblastoma
- Uterine Cervical Neoplasm
- Trematode Infections
Pathways
- Dna Replication
- Response To Oxidative Stress
- Cell Proliferation
- Translation
- Gene Silencing
- Cell Cycle
PTMs
- Cleavage
- Ribosylation
- Phosphorylation
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUDT5
bosterbio.com/bosterbio-gene-info-cards/NUDT5
References
PMID: 10567213 by Gasmi L., et al. Cloning, expression and characterization of YSA1H, a human adenosine 5'-diphosphosugar pyrophosphatase possessing a MutT motif.
PMID: 10722730 by Yang H., et al. Cloning and characterization of a new member of the Nudix hydrolases from human and mouse.