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- Table of Contents
Phosphoglycerate kinase 1 Antibodies
AND PGK1 ELISA kits, Phosphoglycerate kinase 1 Proteins
Many biological assays use antibodies to detect Phosphoglycerate kinase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Phosphoglycerate kinase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Phosphoglycerate kinase 1 antibodies...
Designing a Western blot for Phosphoglycerate kinase 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PGK1 Western Blot GuideDesigning an IHC experiment for Phosphoglycerate kinase 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PGK1 IHC GuidePGK1 Infographic by Boster Bio
All PGK1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PB9774
100 μg/vial
Cat # PB9774
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2045
100 μg/vial
Cat # PA2045
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M01449
100 μl
Cat # M01449
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$405
Cat # A01449
100ul
Cat # A01449
100ul
PGK1 Overview
Facts about Phosphoglycerate kinase 1.
Phosphoglycerate kinase 1 (PGK1)
In addition to its role as a glycolytic enzyme, it seems that PGK-1 functions as a polymerase alpha cofactor protein (primer recognition protein) (PubMed:2324090). May play a role in sperm motility (PubMed:26677959).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PGK1 |
| Uniprot: | P00558 |
| Entrez: | 5230 |
Family
| Belongs to: |
|---|
| phosphoglycerate kinase family |
Alternative Names
Cell migration-inducing gene 10 protein; EC 2.7.2.3; MGC142128; MGC8947; MIG10; PGK1; PGKA; PGKAMGC117307; phosphoglycerate kinase 1; Primer recognition protein 2; PRP 2; PRP2
Molecular Weight
Mass (kDA):
44.615 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq21.1 |
| Sequence: | X; NC_000023.11 (78104248..78129295) |
Tissue Specificity
Mainly expressed in spermatogonia. Localized on the principle piece in the sperm (at protein level). Expression significantly decreased in the testis of elderly men.
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Neoplasms
- Hypoxia
- Carcinoma
- Anemia
- Tumor Angiogenesis
- Neoplasm Metastasis
- Anemia, Hemolytic
- Deficiency Of Phosphoglycerate Kinase
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Menkes Kinky Hair Syndrome
Interacting Proteins
- GAPDH
- HDAC3
- PCNA
Pathways
- Translation
- Glycolysis
- Methylation
- Fermentation
- Secretion
- Angiogenesis
- Localization
- Cell Proliferation
- Mating
- Dna Methylation
- Pathogenesis
- Transport
- Cell Growth
PTMs
- Methylation
- Cleavage
- Phosphorylation
- Hydroxylation
- Decarboxylation
- Acetylation
- Demethylation
Research Areas
- Prostate Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PGK1
bosterbio.com/bosterbio-gene-info-cards/PGK1
References
PMID: 6188151 by Michelson A.M., et al. Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase.
PMID: 2995995 by Michelson A.M., et al. Structure of the human phosphoglycerate kinase gene and the intron- mediated evolution and dispersal of the nucleotide-binding domain.