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- Table of Contents
Designing an IHC experiment for POC1A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the POC1A IHC GuideFacts about POC1 centriolar protein homolog A.
Acts in concert with POC1B to ensure centriole ethics and proper mitotic spindle formation. .
| Human | |
|---|---|
| Gene Name: | POC1A |
| Uniprot: | Q8NBT0 |
| Entrez: | 25886 |

| Belongs to: |
|---|
| WD repeat POC1 family |

DKFZp434C245; MGC131902; PIX2; POC1 centriolar protein homolog A (Chlamydomonas); POC1 centriolar protein homolog A; WD repeat domain 51A; WD repeat-containing protein 51A; WDR51A
Mass (kDA):
45.009 kDA

| Human | |
|---|---|
| Location: | 3p21.2 |
| Sequence: | 3; NC_000003.12 (52075226..52154423, complement) |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Component of both mother and daughter centrioles.




PMID: 18068700 by Hames R.S., et al. Pix1 and Pix2 are novel WD40 microtubule-associated proteins that colocalize with mitochondria in Xenopus germ plasm and centrosomes in human cells.
PMID: 20008567 by Pearson C.G., et al. Basal body stability and ciliogenesis requires the conserved component Poc1.