PPA2 Antibodies

AND PPA2 ELISA kits, PPA2 Proteins

Many biological assays use antibodies to detect PPA2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPA2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPA2 antibodies...

We validate the specificity of these antibodies to PPA2 by testing them on tissues known to express PPA2 positively and negatively. Browse below to find the PPA2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PPA2 Infographic by Boster Bio

All PPA2 Products

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Anti-PPA2 Antibody Picoband®

1 Q&As

Western blot analysis of PPA2 using anti-PPA2 antibody (A06587)

IHC analysis of PPA2 using anti-PPA2 antibody (A06587)

Human, Mouse

ELISA, IF, IHC, ICC, WB

$370
Cat # A06587
100 μg/vial

PPA2 (NM_176869) Human Recombinant Protein

$1249
Cat # PROTQ9H2U2
20 µg

Anti-PPA2 Mouse Monoclonal Antibody [Clone ID: OTI7C1]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPA2 (Right lane) cDNA for 48 hrs and lysed

Human

IHC, WB

$523
Cat # M06587
100 µl

PPA2 (NM_176869) Human Over-expression Lysate

PPA2 Human Over-expression Lysates NM_001034191

Human

$628
Cat # LS027068
20 µg, 100 µg

PPA2 Overview

Facts about Inorganic pyrophosphatase 2, mitochondrial.

PPA2 3D structure. Source: alphafold

Inorganic pyrophosphatase 2, mitochondrial (PPA2)

Hydrolyzes inorganic pyrophosphate (PubMed:27523597). This activity is essential for proper regulation of mitochondrial membrane potential, and mitochondrial organization and function (PubMed:27523598).

Gene Information

Human
Gene Name:	PPA2
Uniprot:	Q9H2U2
Entrez:	27068

Family

Belongs to:

PPase family

Alternative Names

EC 3.6.1.1; FLJ20459; MGC49850; mitochondrial; pyrophosphatase (inorganic) 2

Molecular Weight

Mass (kDA):
37.92 kDA

Genomic Context


Human

Location:	4q24
Sequence:	4; NC_000004.12 (105369077..105474070, complement)

Tissue Specificity

Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.

Subcellular Localizations

Mitochondrion.

Diseases

Neoplasm Metastasis
Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Prostate
Atherosclerosis
Prostatic Neoplasms
Mitochondrial Dna Depletion
Hepatitis, Chronic
Metastatic Malignant Neoplasm To The Lymph Node
Hepatitis C, Chronic
Benign Prostatic Hypertrophy
Carcinoma

Hypokinesia
Insulin Resistance
Immunologic Deficiency Syndromes
Cardiovascular Diseases
Metastatic Prostate Cancer
Nervousness
Dysmyelopoietic Syndromes

Pathways

Cell Cycle
Cytokinesis
Mitosis
Transport
Cell Division
Interphase
Cell Growth
Protein Phosphorylation
Hyperphosphorylation
Habituation
Virulence
Anaphase
Cell Cycle Arrest

Reverse Transcription
Regulation Of Mitosis
Mating
Cell Morphogenesis
Regulation Of Cytokinesis
Exocytosis
Hormone Secretion

PTMs

Phosphorylation

Hydroxylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPA2

References

PMID: 15210126 by Afjehi-Sadat L., et al. Hypothetical proteins with putative enzyme activity in human amnion, lymphocyte, bronchial epithelial and kidney cell lines.

PMID: 27523598 by Guimier A., et al. Biallelic PPA2 mutations cause sudden unexpected cardiac arrest in infancy.