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- Table of Contents
Designing an IHC experiment for PPP1R1A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PPP1R1A IHC GuideFacts about Protein phosphatase 1 regulatory subunit 1A.
Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins which are not directly phosphorylated by PKA.
| Human | |
|---|---|
| Gene Name: | PPP1R1A |
| Uniprot: | Q13522 |
| Entrez: | 5502 |

| Belongs to: |
|---|
| protein phosphatase inhibitor 1 family |

Protein phosphatase 1 regulatory subunit 1A
Mass (kDA):
19.011 kDA

| Human | |
|---|---|
| Location: | 12q13.2 |
| Sequence: | 12; NC_000012.12 (54579246..54588659, complement) |


PMID: 8611507 by Endo S., et al. Multiple structural elements define the specificity of recombinant human inhibitor-1 as a protein phosphatase-1 inhibitor.
PMID: 11564868 by Connor J.H., et al. Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.