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- Table of Contents
PRKD3 Antibodies
AND PRKD3 ELISA kits, PRKD3 Proteins
Many biological assays use antibodies to detect PRKD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKD3 antibodies...
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PRKD3 Infographic by Boster Bio
All PRKD3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$523
Cat # M07092
100 µl
Cat # M07092
100 µl
PRKD3 Overview
Facts about Serine/threonine-protein kinase D3.
Serine/threonine-protein kinase D3 (PRKD3)
Converts transient diacylglycerol (DAG) signs into prolonged physiological consequences, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PRKD3 |
| Uniprot: | O94806 |
| Entrez: | 23683 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
EC 2.7.11; EC 2.7.11.13; EPK2; EPK2PKD3; nPKC nu; nPKC-nu; PKC nu; PKC-NU; PRKCN; PRKCNnPKC-NU; PRKD3; Protein kinase C nu type; protein kinase C, nu; protein kinase D3; Protein kinase EPK2; protein-serine/threonine kinase; serine/threonine-protein kinase D3
Molecular Weight
Mass (kDA):
100.471 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p22.2 |
| Sequence: | 2; NC_000002.12 (37250502..37324833, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Mutation Abnormality
- Malignant Squamous Cell Neoplasm
- Lung Neoplasms
- Melanoma
- Bone Neoplasms
- Malignant Neoplasm Of Lung
- Metastatic Malignant Neoplasm To The Bone
Interacting Proteins
- VAMP2
Pathways
- Drug Resistance
- Cell Killing
- Cell Cycle
- Bone Resorption
PTMs
Research Areas
- Cancer
- Diabetes Research
- GPCR
- Protein Kinase
- Signal Transduction
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKD3
bosterbio.com/bosterbio-gene-info-cards/PRKD3
References
PMID: 10231560 by Hayashi A., et al. PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu.
PMID: 18076381 by Chen J., et al. Selective binding of phorbol esters and diacylglycerol by individual C1 domains of the PKD family.