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- Table of Contents
PSMD1 Antibodies
AND PSMD1 ELISA kits, PSMD1 Proteins
Many biological assays use antibodies to detect PSMD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PSMD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PSMD1 antibodies...
Designing a Western blot for PSMD1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PSMD1 Western Blot GuideDesigning an IHC experiment for PSMD1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PSMD1 IHC GuidePSMD1 Infographic by Boster Bio
All PSMD1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06293-1
100 μg/vial
Cat # A06293-1
100 μg/vial
Anti-POH1/PSMD14 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A06584-1
100 µg/vial
Cat # A06584-1
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, WB
$370
Cat # A09882-1
100 µg/vial
Cat # A09882-1
100 µg/vial
Human
ELISA, Flow Cytometry, WB
$370
Cat # A03169-2
100 μg/vial
Cat # A03169-2
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M06584
100 μl/vial
Cat # M06584
100 μl/vial
Human
$628
Cat # LS005718
20 µg, 100 µg
Cat # LS005718
20 µg, 100 µg
PSMD1 Overview
Facts about 26S proteasome non-ATPase regulatory subunit 1.
26S proteasome non-ATPase regulatory subunit 1 (PSMD1)
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays an integral role in the maintenance of protein homeostasis by eliminating misfolded or damaged proteins, which might impair cellular capabilities, and by eliminating proteins whose functions are no longer required.
Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. .
Gene Information
| Human | |
|---|---|
| Gene Name: | PSMD1 |
| Uniprot: | Q99460 |
| Entrez: | 5707 |
Family
| Belongs to: |
|---|
| proteasome subunit S1 family |
Alternative Names
26S proteasome non-ATPase regulatory subunit 1; 26S proteasome regulatory subunit RPN2; 26S proteasome regulatory subunit S1; 26S proteasome subunit p112; MGC133040; MGC133041; P112; proteasome (prosome, macropain) 26S subunit, non-ATPase, 1; Rpn2; S1
Molecular Weight
Mass (kDA):
105.836 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q37.1 |
| Sequence: | 2; NC_000002.12 (231056864..231172827) |
Diseases
- Malignant Neoplasms
- Leukemia
- Neoplasms
- Acute Promyelocytic Leukemia
- Radiation Injury
- Malignant Neoplasm Of Prostate
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Breast
- Malignant Neoplasm Of Brain
- Glioma
- Gastrointestinal Hemorrhage
- Brain Neoplasms
Interacting Proteins
- Adrm1
Pathways
- Proteolysis
- Reverse Transcription
- Cell Cycle
- Cell Death
- Oxidative Phosphorylation
- Protein Unfolding
- Glycolysis
PTMs
- Phosphorylation
Research Areas
- Cell Cycle and Replication
- Neuroscience
- Ubiquitin Proteasome Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSMD1
bosterbio.com/bosterbio-gene-info-cards/PSMD1
References
PMID: 8816993 by Yokota K., et al. cDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p.
PMID: 1317798 by Kanayama H.O., et al. Demonstration that a human 26S proteolytic complex consists of a proteasome and multiple associated protein components and hydrolyzes ATP and ubiquitin-ligated proteins by closely linked mechanisms.