PTCHD1 Antibodies

AND PTCHD1 ELISA kits, PTCHD1 Proteins

Many biological assays use antibodies to detect PTCHD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTCHD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTCHD1 antibodies...

We validate the specificity of these antibodies to PTCHD1 by testing them on tissues known to express PTCHD1 positively and negatively. Browse below to find the PTCHD1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: MAGEB10

PTCHD1 Infographic by Boster Bio

All PTCHD1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

PTCHD1 Overview

Facts about Patched domain-containing protein 1.

PTCHD1 3D structure. Source: alphafold

Patched domain-containing protein 1 (PTCHD1)

Required for the development and function of the thalamic reticular nucleus (TRN), a component of the thalamus that is critical for thalamocortical transmission, creation of sleep rhythms, sensorimotor processing and attention. .

Gene Information

Human
Gene Name:	PTCHD1
Uniprot:	Q96NR3
Entrez:	139411

Family

Belongs to:

patched family

Alternative Names

FLJ30296; MGC149798; patched domain containing 1; patched domain-containing protein 1

Molecular Weight

Mass (kDA):
101.341 kDA

Genomic Context


Human

Location:	Xp22.11
Sequence:	X; NC_000023.11 (23334369..23404374)

Tissue Specificity

Widely expressed, including in various regions of the brain with highest expression in the gray and white cerebellum, followed by the cerebellar vermis and the pituitary gland.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Autistic Disorder
Autism Spectrum Disorders
Child Development Disorders, Pervasive
Learning Disabilities
Malnutrition
Rett Syndrome
Schizophrenia
Nervous System Disorder
Speech Delay
Nervousness

Chromosomal Translocation
Chromosome Breakage
Attention Deficit Hyperactivity Disorder
Cytogenetic Abnormality

Pathways

System Development
Nervous System Development

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTCHD1

References

PMID: 20844286 by Noor A., et al. Disruption at the PTCHD1 Locus on Xp22.11 in Autism spectrum disorder and intellectual disability.

PMID: 25131214 by Chaudhry A., et al. Phenotypic spectrum associated with PTCHD1 deletions and truncating mutations includes intellectual disability and autism spectrum disorder.