Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (Ptpmt1)

Lipid phosphatase that dephosphorylates phosphatidylglycerophosphate (PGP) into phosphatidylglycerol (PG) (By similarity). PGP is a crucial intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (By similarity).

Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (PubMed:16039589). Has probably a taste for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (PubMed:16039589).