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We validate the specificity of these antibodies to Poliovirus receptor by testing them on tissues known to express PVR positively and negatively. Browse below to find the PVR antibody that suites your experiment. We have 10 of these antibodies and many publications and validation images.
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Facts about Poliovirus receptor.
These interactions accumulates at the cell-cell contact site, leading to the creation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and trigger cytoxicity of activated NK cells.
CD155 antigen; CD155; HVED; NECL5; Necl-5; nectin-like 5; Nectin-like protein 5; poliovirus receptor; PVR; PVS; PVSFLJ25946; Tage4
|Sequence:||19; NC_000019.10 (44643798..44666162)|
[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein.; [Isoform Delta]: Cell membrane; Single-pass type I membrane protein.; [Isoform Beta]: Secreted.; [Isoform Gamma]: Secreted.
The Poliovirus receptor (also known as PVR) is a cell adhesion molecule. Its sequence domain ranges from 21-343 aa. The PVR marker is versatile and can be utilized in SDS-PAGE as well other biochemical studies. This reagent is stable when stored at 2-8°C for up to one week. Additionally, it can be stored at temperatures ranging from -20degC to 80degC for storage over the long term. Avoid repeated freeze-thaw cycles to guarantee optimal storage. All scientists across the globe can participate in the Boster Bio program.
The Poliovirus receptor (also called CD155) is a transmembrane-specific protein encoded by the PVR gene. It is part of the immunoglobulin superfamily. The CD155 protein's transmembrane molecule mediates cell attachment to vitronectin. In addition, its intracellular domain is in contact and communicates with Tctex-1DYNLT1, light chains of dynein Tctex-1DYNLT1 along with Tctex-2. This gene is unique to the primate lineage, and has multiple transcript variants resulting in different isoforms. Boster Bio's antibodies against the Poliovirus receptor have been tested against positive and negative samples to ensure they work in the manner expected.
The Boster Bio PVR cell adhesion protein targets a gene known as PVR cell adhesion molecule. This protein is overexpressed in human malignant tumors , and acts as a major immunoevasion factor which contributes to the growth of tumors and metastasis. The anti-PVR antibody offers several advantages for researchers. Anti-PVR antibodies provide specificity for immunogen, applications and specificity.
PVR plays a number of important roles in the immune system. It interacts with CD226 and TIGIT to stimulate the immune system. PVR is used in clinical trials to treat cancer by recruiting N cells and CD8+. PVR has many other functions that are still undiscovered. Further research is required to uncover them. Here are three of the greatest uses of the PVR gene.
Two transmembrane protein genes are encoded by the PVR gene both PVRa and PVRd. PVRa includes the entire first six exons, whereas PVRd employs an alternative splice site to incorporate additional nucleotides at the end of exon 6. Each encoded protein contains eight distinct amino acids. It also interacts with regulator proteins to enable distinct localizations in polarized cells.
The CD155 protein is encoded by the gene PVR. It is a transmembrane glyprotein from the immunoglobulins family. Its extracellular domain facilitates the cell's attachment to vitronectin while its intracellular domain interacts with the Tctex-1DYNLT1 light chain dynein. Its gene is highly conserved in primate specieslicati offersmultiple transcript variants resurimantsoull attaage,sp>
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