RABGAP1 Antibodies

AND RABGAP1 ELISA kits, RABGAP1 Proteins

Many biological assays use antibodies to detect RABGAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RABGAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RABGAP1 antibodies...

We validate the specificity of these antibodies to RABGAP1 by testing them on tissues known to express RABGAP1 positively and negatively. Browse below to find the RABGAP1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RABGAP1 Infographic by Boster Bio

All RABGAP1 Products

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Anti-RABGAP1 Antibody

Western blot analysis of extracts of various cell lines, using RABGAP1 antibody at 1:1000 dilution

Immunohistochemistry of paraffin-embedded Human colon carcinoma using RABGAP1 Rabbit pAb at dilution of 1:100

Immunohistochemistry of paraffin-embedded Mouse testis using RABGAP1 Rabbit pAb at dilution of 1:100

Human, Mouse

IHC, WB

$405
Cat # A09466
100ul

RABGAP1 Overview

Facts about Rab GTPase-activating protein 1.

RABGAP1 3D structure. Source: alphafold

Rab GTPase-activating protein 1 (RABGAP1)

May act as a GTPase-activating protein of RAB6A.
May play a role in microtubule nucleation by centrosome.

May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition. .

Gene Information

Human
Gene Name:	RABGAP1
Uniprot:	Q9Y3P9
Entrez:	23637

Family

Belongs to:

No superfamily

Alternative Names

DKFZp586D2123; GAP and centrosome-associated protein; GAPCENA; RAB GTPase activating protein 1; rab GTPase-activating protein 1; rab6 GTPase activating protein (GAP and centrosome-associated); Rab6 GTPase activating protein, GAPCenA; Rab6 GTPase-activating protein GAPCenA; RP11-123N4.2; TBC1 domain family, member 11; TBC1D11

Molecular Weight

Mass (kDA):
121.737 kDA

Genomic Context


Human

Location:	9q33.2-q33.3
Sequence:	9; NC_000009.12 (122931640..123104869)

Subcellular Localizations

Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Predominantly cytosolic but also associated with the centrosome.

Diseases

Neoplasms
Malignant Tumor Of Colon
Glaucoma, Open-angle
Tissue Adhesions
Retinitis Pigmentosa
Neurofibromatoses
Bardet-biedl Syndrome
Glaucoma
Polycystic Kidney, Autosomal Dominant
Polycystic Kidney Diseases

Malignant Neoplasms
Neurofibromatosis 2
Kidney Diseases
Chimera Disorder
Primary Open Angle Glaucoma

Interacting Proteins

GABARAPL1

Pathways

Transport
Cell Cycle
Cell Adhesion
Intracellular Transport
Mitosis
Metaphase
Endocytosis
Ovulation
Localization
Regeneration
Microtubule Nucleation

Spindle Checkpoint
Tissue Regeneration
Cell Death
S Phase
Luteinization
Exocytosis

PTMs

Phosphoprotein

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RABGAP1

References

PMID: 10202141 by Cuif M.-H., et al. Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome.

PMID: 19077034 by Ishibashi K., et al. Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.