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DNA-binding protein SATB1 Antibodies
AND SATB1 ELISA kits, DNA-binding protein SATB1 Proteins
Many biological assays use antibodies to detect DNA-binding protein SATB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNA-binding protein SATB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNA-binding protein SATB1 antibodies...
Designing a Western blot for DNA-binding protein SATB1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SATB1 Western Blot GuideDesigning an IHC experiment for DNA-binding protein SATB1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SATB1 IHC GuideSATB1 Infographic by Boster Bio
All SATB1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, ICC, WB
$370
Cat # A01312-1
100 μg/vial
Cat # A01312-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01312
100 μl
Cat # M01312
100 μl
Human
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01317-1
100 μl
Cat # M01317-1
100 μl
SATB1 Overview
Facts about DNA-binding protein SATB1.
DNA-binding protein SATB1 (SATB1)
Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to comprehend the sugar-phosphate arrangement of double-stranded DNA.
Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for many chromatin remodeling enzymes (e.
Gene Information
| Human | |
|---|---|
| Gene Name: | SATB1 |
| Uniprot: | Q01826 |
| Entrez: | 6304 |
Family
| Belongs to: |
|---|
| CUT homeobox family |
Alternative Names
DNA-binding protein SATB1; SATB homeobox 1; SATB1; special AT-rich sequence binding protein 1 (binds to nuclearmatrix/scaffold-associating DNA's); Special AT-rich sequence-binding protein 1
Molecular Weight
Mass (kDA):
85.957 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p24.3 |
| Sequence: | 3; NC_000003.12 (18345377..18445592, complement) |
Tissue Specificity
Expressed predominantly in thymus.
Subcellular Localizations
Nucleus matrix. Nucleus, PML body. Organized into a cage-like network anchoring loops of heterochromatin and tethering specialized DNA sequences. When sumoylated, localized in promyelocytic leukemia nuclear bodies (PML NBs).
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Mammary Neoplasms
- Carcinoma
- Malignant Neoplasm Of Breast
- Malignant Paraganglionic Neoplasm
- Lymphoma
- Metastatic Malignant Neoplasm To The Lymph Node
- Acute Erythroblastic Leukemia
- Lymphatic Metastasis
- Carcinogenesis
Interacting Proteins
- CASP6
- CTNNB1
- SUMO1
- SUMO1P1
Pathways
- Chromatin Remodeling
- Cell Differentiation
- Chromatin Organization
- Localization
- Pathogenesis
- Cell Cycle
- Cell Development
- Methylation
- Histone Acetylation
- Cell Proliferation
- Cell Death
- Dna Replication
- Proteolysis
PTMs
- Acetylation
- Methylation
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SATB1
bosterbio.com/bosterbio-gene-info-cards/SATB1
References
PMID: 1505028 by Dickinson L.A., et al. A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition.
PMID: 9111059 by Dickinson L.A., et al. An atypical homeodomain in SATB1 promotes specific recognition of the key structural element in a matrix attachment region.
3 Publications of Boster DNA-binding protein SATB1 Antibodies & ELISA Kits
- PubMed ID: 34112915, Noda K,Philips BJ,Snyder ME,Phillippi JA,Sullivan M,Stolz DB,Ren X,Luketich JD,S...
- PubMed ID: 27343265, Localization of corin and atrial natriuretic peptide expression in human renal s...
- PubMed ID: 24235832, Inhibition of choriocarcinoma by Fe3O4-dextran-anti-?-human chorionic gonadotrop...
*More publications can be found for each product on its corresponding product page