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- Table of Contents
SLC16A1 Antibodies
AND SLC16A1 ELISA kits, SLC16A1 Proteins
Many biological assays use antibodies to detect SLC16A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC16A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC16A1 antibodies...
Designing a Western blot for SLC16A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC16A1 Western Blot GuideDesigning an IHC experiment for SLC16A1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SLC16A1 IHC GuideSLC16A1 Infographic by Boster Bio
All SLC16A1 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS006566
20 µg, 100 µg
Cat # LS006566
20 µg, 100 µg
Human
$628
Cat # LS151473
20 µg, 100 µg
Cat # LS151473
20 µg, 100 µg
SLC16A1 Overview
Facts about Monocarboxylate transporter 1.
Monocarboxylate transporter 1 (SLC16A1)
Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.
Depending upon the tissue and on cicumstances, mediates the export or import of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet.
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC16A1 |
| Uniprot: | P53985 |
| Entrez: | 6566 |
Family
| Belongs to: |
|---|
| major facilitator superfamily |
Alternative Names
FLJ36745; HHF7; MCT 1; MCT; MCT1; MCT1MGC44475; member 1; monocarboxylate transporter 1; SLC16A1; Solute carrier family 16 member 1; solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
Molecular Weight
Mass (kDA):
53.944 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.2 |
| Sequence: | 1; NC_000001.11 (112911847..112956196, complement) |
Tissue Specificity
Detected in heart and in blood lymphocytes and monocytes (at protein level). Widely expressed.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Hyperinsulinism
- Hypoglycemia
- Persistent Hyperinsulinemia Hypoglycemia Of Infancy
- Neoplasms
- Brain Injuries
- Insulinoma
- Malignant Neoplasms
- Diabetes Mellitus
- Developmental Delay (disorder)
- Beckwith-wiedemann Syndrome
- Fetal Growth Retardation
- Epilepsy
Pathways
- Transport
- Secretion
- Insulin Secretion
- Glycolysis
- Localization
- Immune Response
- Drug Transport
- Cell Death
- Cell Adhesion
- Cell Cycle Arrest
- Cell Cycle
- Cell Proliferation
- Glycosylation
PTMs
- Carboxylation
- Glycosylation
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC16A1
bosterbio.com/bosterbio-gene-info-cards/SLC16A1
References
PMID: 7835905 by Garcia C.K., et al. cDNA cloning of the human monocarboxylate transporter 1 and chromosomal localization of the SLC16A1 locus to 1p13.2-p12.
PMID: 11944921 by Cuff M.A., et al. The human monocarboxylate transporter, MCT1: genomic organization and promoter analysis.