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SLC25A24 Antibodies
AND SLC25A24 ELISA kits, SLC25A24 Proteins
Many biological assays use antibodies to detect SLC25A24, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC25A24 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC25A24 antibodies...
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SLC25A24 Infographic by Boster Bio
All SLC25A24 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A08355-1
100 μg/vial
Cat # A08355-1
100 μg/vial
SLC25A24 Overview
Facts about Calcium-binding mitochondrial carrier protein SCaMC-1.
Calcium-binding mitochondrial carrier protein SCaMC-1 (SLC25A24)
Calcium-dependent mitochondrial solute carrier. Mediates the reversible, electroneutral exchange of Mg-ATP or Mg-ADP against phosphate ions, catalyzing the net uptake or efflux of adenine nucleotides across the mitochondrial inner membrane.
Nucleotide transport is dormant when cytosolic calcium levels are low, and is triggered by an increase in cytosolic calcium levels. May play a role in protecting cells from oxidative stress- induced cell death, probably by promoting the formation of calcium-phosphate precipitates from the mitochondrial matrix, and thereby buffering calcium levels in the mitochondrial matrix.
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC25A24 |
| Uniprot: | Q6NUK1 |
| Entrez: | 29957 |
Family
| Belongs to: |
|---|
| mitochondrial carrier (TC 2.A.29) family |
Alternative Names
APC1calcium-binding mitochondrial carrier protein SCaMC-1; calcium-binding transporter; DKFZp586G0123; MCSC1; Mitochondrial ATP-Mg/Pi carrier protein 1; mitochondrial ATP-Mg/Pi transporter; Mitochondrial Ca(2+)-dependent solute carrier protein 1; SCAMC1; SCAMC-1; short calcium-binding mitochondrial carrier 1; Small calcium-binding mitochondrial carrier protein 1; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24; Solute carrier family 25 member 24
Molecular Weight
Mass (kDA):
53.354 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.3 |
| Sequence: | 1; NC_000001.11 (108134043..108200343, complement) |
Tissue Specificity
Present in various cell lines (at protein level). Expressed in all tissues tested. Highly expressed in testis, expressed at intermediate level in small intestine and pancreas, and weakly expressed in kidney, spleen, liver, skeletal muscle and heart.
Subcellular Localizations
Mitochondrion inner membrane; Multi-pass membrane protein.
Diseases
- Autistic Disorder
- Malignant Neoplasms
- Neoplasms
- Autism Spectrum Disorders
Pathways
- Transport
- Nucleotide Transport
- Protein Complex Assembly
- Translation
- Adenine Nucleotide Transport
- Cell Death
- Mitochondrial Translation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC25A24
bosterbio.com/bosterbio-gene-info-cards/SLC25A24
References
PMID: 15054102 by del Arco A., et al. Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains.
PMID: 15123600 by Fiermonte G., et al. Identification of the mitochondrial ATP-Mg/Pi transporter. Bacterial expression, reconstitution, functional characterization, and tissue distribution.