Slit homolog 1 protein (SLIT1)

Thought to act as molecular guidance cue in cellular migration, and function seems to be mediated by interaction with roundabout homolog receptors. During neural development involved in axonal navigation at the ventral midline of the neural tube and projection of axons to different areas (By similarity).

SLIT1 and SLIT2 together appear to be essential for midline guidance in the forebrain by acting as gruesome signal preventing inappropriate midline crossing by axons projecting from the olfactory bulb. .