STK10 Antibodies

AND STK10 ELISA kits, STK10 Proteins

Many biological assays use antibodies to detect STK10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STK10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STK10 antibodies...

We validate the specificity of these antibodies to STK10 by testing them on tissues known to express STK10 positively and negatively. Browse below to find the STK10 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STK10 Infographic by Boster Bio

All STK10 Products

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Anti-LOK STK10 Antibody

5 Q&As

Immunohistochemical analysis of paraffin-embedded human liver cancer

Western Blot analysis of HuvEc cells using LOK Polyclonal Antibody

Western blot analysis of the lysates from HT-29 cells using STK10 antibody

Human, Mouse, Rat

ELISA, IHC, WB

$399
Cat # A06406
100μl

LOK (STK10) (NM_005990) Human Over-expression Lysate

Human

$628
Cat # LS006793
20 µg, 100 µg

STK10 Overview

Facts about Serine/threonine-protein kinase 10.

STK10 3D structure. Source: alphafold

Serine/threonine-protein kinase 10 (STK10)

Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and maybe PLK1.

Involved in regulation of lymphocyte migration from mediating phosphorylation of ERM proteins like MSN. Acts as a negative regulator of MAP3K1/MEKK1.

Gene Information

Human
Gene Name:	STK10
Uniprot:	O94804
Entrez:	6793

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11; EC 2.7.11.1; LOKserine/threonine-protein kinase 10; Lymphocyte-oriented kinase; PRO2729; serine/threonine kinase 10

Molecular Weight

Mass (kDA):
112.135 kDA

Genomic Context


Human

Location:	5q35.1
Sequence:	5; NC_000005.10 (172042074..172188224, complement)

Tissue Specificity

Highly expressed in rapidly proliferating tissues (spleen, placenta, and peripheral blood leukocytes). Also expressed in brain, heart, skeletal muscle, colon, thymus, kidney, liver, small intestine and lung.

Subcellular Localizations

Cell membrane; Peripheral membrane protein.

Diseases

Neoplasms
Malignant Neoplasms
Tissue Adhesions
Neoplasm Metastasis
Seminoma
Aneuploidy
Sarcoma
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Neoplasms, Germ Cell And Embryonal
Ventricular Septal Defects
Pancreatic Neoplasm
Asthma

Radial Polydactyly
Malignant Neoplasm Of Pancreas
Adenocarcinoma
Dermatitis
Testicular Neoplasms
Congenital Abnormality
Mild Mental Retardation

Pathways

Hypersensitivity
Cell Adhesion
Cell Migration
Cell Cycle
Cell Development
Lymphocyte Migration
Localization
Limb Development

Lymphocyte Activation
Secretion

PTMs

Phosphorylation

Methylation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STK10

References

PMID: 10199912 by Kuramochi S., et al. Molecular cloning of the human gene STK10 encoding lymphocyte- oriented kinase, and comparative chromosomal mapping of the human, mouse, and rat homologues.

PMID: 11903060 by Tao L., et al. Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells.