Symplekin Antibodies

AND SYMPK ELISA kits, Symplekin Proteins

Many biological assays use antibodies to detect Symplekin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Symplekin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Symplekin antibodies...

We validate the specificity of these antibodies to Symplekin by testing them on tissues known to express SYMPK positively and negatively. Browse below to find the SYMPK antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SYMPK Infographic by Boster Bio

All SYMPK Products

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Specificity

Applications

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Anti-Symplekin SYMPK Antibody

Western blot analysis of extracts of various cell lines, using SYMPK antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A05709
100ul

Symplekin (SYMPK) (NM_004819) Human Recombinant Protein

Coomassie blue staining of purified SYMPK protein

$1062
Cat # PROTQ92797
20 µg

Symplekin (SYMPK) (NM_004819) Human Over-expression Lysate

Human

$960
Cat # LS008189
20 µg, 100 µg

Anti-Symplekin/SYMPK Antibody Picoband®

Western blot analysis of Symplekin/SYMPK using anti-Symplekin/SYMPK antibody (A05709-1)

IHC analysis of Symplekin/SYMPK using anti-Symplekin/SYMPK antibody (A05709-1)

Human, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05709-1
100 µg/vial

SYMPK Overview

Facts about Symplekin.

SYMPK 3D structure. Source: alphafold

Symplekin (SYMPK)

Scaffold protein that functions as a component of a multimolecular complex involved in histone mRNA 3'-end processing. Specific component of the tight junction (TJ) plaque, but may not be a completely junctional component.

May have a home - keeping rule. Is involved in pre-mRNA polyadenylation.

Gene Information

Human
Gene Name:	SYMPK
Uniprot:	Q92797
Entrez:	8189

Family

Belongs to:

Symplekin family

Alternative Names

FLJ27092; SPKSYM; symplekin

Molecular Weight

Mass (kDA):
141.148 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45815410..45863167, complement)

Tissue Specificity

In testis, expressed in polar epithelia and Sertoli cells but not in vascular endothelia. The protein is detected in stomach, duodenum, pancreas, liver, fetal brain, carcinomas, lens-forming cells, fibroblasts, lymphocytes, lymphoma cells, erythroleukemia cells but not in endothelium of vessels, epidermis, intercalated disks, Purkinje fiber cells of the heart and lymph node.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell junction, tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Nucleus, nucleoplasm. Cytoplasmic face of adhesion plaques (major) and nucleoplasm (minor) (in cells with TJ). Nucleoplasm (in cells without TJ). Nuclear bodies of heat-stressed cells. Colocalizes with HSF1 in nuclear stress bodies upon heat shock (PubMed:14707147).