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- Table of Contents
Designing an IHC experiment for UBE2G1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the UBE2G1 IHC Guide
Facts about Ubiquitin-conjugating enzyme E2 G1.
May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4.
| Human | |
|---|---|
| Gene Name: | UBE2G1 |
| Uniprot: | P62253 |
| Entrez: | 7326 |

| Belongs to: |
|---|
| ubiquitin-conjugating enzyme family |

E217K; EC 6.3.2.19; UBC7; UBE2G1; UBE2GE217K; Ubiquitin carrier protein G1; ubiquitin-conjugating enzyme E2 G1; ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); Ubiquitin-protein ligase G1
Mass (kDA):
19.509 kDA

| Human | |
|---|---|
| Location: | 17p13.2 |
| Sequence: | 17; NC_000017.11 (4269217..4366674, complement) |
Widely expressed, mainly in skeletal muscle.




PMID: 8893823 by Watanabe T.K., et al. Molecular cloning of UBE2G, encoding a human skeletal muscle-specific ubiquitin-conjugating enzyme homologous to UBC7 of C. elegans.
PMID: 19103148 by Pabarcus M.K., et al. CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases.