Ubinuclein-1 Antibodies

AND UBN1 ELISA kits, Ubinuclein-1 Proteins

Many biological assays use antibodies to detect Ubinuclein-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ubinuclein-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ubinuclein-1 antibodies...

We validate the specificity of these antibodies to Ubinuclein-1 by testing them on tissues known to express UBN1 positively and negatively. Browse below to find the UBN1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UBN1 Infographic by Boster Bio

All UBN1 Products

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Anti-UBN-1 Antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Ubinuclein Antibody

Immunofluorescence analysis of A549 cells, using Ubinuclein Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A07807
100ul

UBN1 (NM_001079514) Human Over-expression Lysate

Human

$960
Cat # LS029855
20 µg, 100 µg

UBN1 Overview

Facts about Ubinuclein-1.

UBN1 3D structure. Source: alphafold

Ubinuclein-1 (UBN1)

Acts as a novel regulator of senescence. Involved in the creation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes.

Binds to proliferation-promoting genes. May be necessary for replication- independent chromatin assembly.

Gene Information

Human
Gene Name:	UBN1
Uniprot:	Q9NPG3
Entrez:	29855

Family

Belongs to:

ubinuclein family

Alternative Names

HIRA-binding protein; ubinuclein 1; ubinuclein-1; VT; VT4

Molecular Weight

Mass (kDA):
121.52 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (4846665..4882401)

Tissue Specificity

Ubiquitous. Also expressed in numerous tumors and cancer cell lines.

Subcellular Localizations

Nucleus, nucleoplasm. Nucleus, PML body. Cell junction, tight junction. Localized as a nuclear speckled-like pattern in proliferating primary fibroblasts. Colocalizes with HIRA, PML and SP100 in PML bodies of senescent cells. Colocalizes with TJP1 and CLDN1. Detected along the upper granular cell layer of epidermis. When overexpressed, accumulates in the nucleus in cells showing defective cytokinesis.