UGT2B15 Antibodies

AND UGT2B15 ELISA kits, UGT2B15 Proteins

Many biological assays use antibodies to detect UGT2B15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGT2B15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGT2B15 antibodies...

We validate the specificity of these antibodies to UGT2B15 by testing them on tissues known to express UGT2B15 positively and negatively. Browse below to find the UGT2B15 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGT2B15 Infographic by Boster Bio

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UGT2B15 Overview

Facts about UDP-glucuronosyltransferase 2B15.

UGT2B15 3D structure. Source: alphafold

UDP-glucuronosyltransferase 2B15 (UGT2B15)

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme displays activity toward several classes of xenobiotic substrates, including simple phenolic compounds, 7-hydroxylated coumarins, flavonoids, anthraquinones, and certain drugs and their hydroxylated metabolites.

It also catalyzes the glucuronidation of endogenous estrogens and androgens. .

Gene Information

Human
Gene Name:	UGT2B15
Uniprot:	P54855
Entrez:	7366

Family

Belongs to:

UDP-glycosyltransferase family

Alternative Names

EC 2.4.1; EC 2.4.1.17; HLUG4; UDP glucuronosyltransferase 2 family, polypeptide B15; UDP glycosyltransferase 2 family, polypeptide B15; UDP glycosyltransferase 2B15; UDP-glucuronosyltransferase 2B15; UDP-glucuronosyltransferase 2B8; UDP-glucuronosyltransferase UGT2B15; UDP-glucuronyltransferase, family 2, beta-15; UDPGT 2B15; UDPGT 2B8; UDPGTH3; UDPGTh-3; UGT2B8UDPGT2B15

Molecular Weight

Mass (kDA):
61.036 kDA

Genomic Context


Human

Location:	4q13.2
Sequence:	4; NC_000004.12 (68646597..68670652, complement)

Tissue Specificity

Expressed in many tissues. Present in liver, prostate and testis.

Subcellular Localizations

Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Carcinoma
Mammary Neoplasms
Hyperplasia
Neoplasms, Hormone-dependent
Myeloproliferative Syndrome, Transient
Neoplasm Metastasis
Headache

Dysequilibrium Syndrome
Prostatic Hyperplasia
Gilbert Disease (disorder)
Carcinogenesis
Allelic Imbalance
Gingival Hyperplasia
Adenoma

Pathways

Conjugation
Excretion
Localization
Transport
Sulfation
Cell Proliferation
Glycosylation
Cell Growth
Translation
Cell Differentiation
Rna Interference
Regulation Of Gene Expression

Protein Glycosylation
Drug Resistance
Gene Conversion
Reverse Transcription
Cellular Localization
Dna Modification
Peptide Secretion

PTMs

Glycosylation

Sulphation

Hydroxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGT2B15

References

PMID: 8399210 by Chen F., et al. Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms.

PMID: 7835232 by Green M.D., et al. Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates.