Uromodulin Antibodies

AND UMOD ELISA kits, Uromodulin Proteins

Many biological assays use antibodies to detect Uromodulin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Uromodulin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Uromodulin antibodies...

We validate the specificity of these antibodies to Uromodulin by testing them on tissues known to express UMOD positively and negatively. Browse below to find the UMOD antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: UCK2

UMOD Infographic by Boster Bio

All UMOD Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human Uromodulin/umod ELISA Kit PicoKine®

9 Q&As

Human

ELISA

$499
Cat # EK1690
96 wells/kit, with removable strips.

Anti-THP UMOD Antibody

Western blot analysis of extracts of various cell lines, using UMOD Antibody at 1:1000 dilution

Human, Mouse

$405
Cat # A01303
100ul

Anti-UMOD Antibody Picoband®

Western blot analysis of UMOD using anti-UMOD antibody (A01303-2)

IHC analysis of Uromodulin/UMOD using anti-Uromodulin/UMOD antibody (A01303-2)

IHC analysis of UMOD using anti UMOD antibody (A01303-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A01303-2
100 μg/vial

Uromucoid (UMOD) (NM_001008389) Human Over-expression Lysate

Human

$960
Cat # LS007369
20 µg, 100 µg

UMOD Overview

Facts about Uromodulin.

UMOD 3D structure. Source: alphafold

Uromodulin (UMOD)

Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes creation of complex filamentous gel-like structure which may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF (PubMed:3498215).

Facilitates neutrophil migration across renal epithelia (PubMed:20798515). .

Gene Information

Human
Gene Name:	UMOD
Uniprot:	P07911
Entrez:	7369

Family

Belongs to:

No superfamily

Alternative Names

ADMCKD2; FJHN; HNFJ; HNFJ1; MCKD2; Tamm-Horsfall glycoprotein; Tamm-Horsfall urinary glycoprotein; THGP; THP; UMOD; uromodulin (uromucoid, Tamm-Horsfall glycoprotein); Uromodulin; Uromucoid

Molecular Weight

Mass (kDA):
69.761 kDA

Genomic Context


Human

Location:	16p12.3
Sequence:	16; NC_000016.10 (20333051..20356301, complement)

Tissue Specificity

Expressed in the tubular cells of the kidney. Most abundant protein in normal urine (at protein level). Synthesized exclusively in the kidney. Expressed exclusively by epithelial cells of the thick ascending limb of Henle's loop (TALH) and of distal convoluted tubule lumen.

Subcellular Localizations

Apical cell membrane; Lipid-anchor, GPI-anchor. Basolateral cell membrane; Lipid-anchor, GPI-anchor. Cell projection, cilium membrane. Only a small fraction sorts to the basolateral pole of tubular epithelial cells compared to apical localization (PubMed:22776760). Secreted into urine after cleavage (PubMed:18375198, PubMed:26811476). Colocalizes with NPHP1 and KIF3A (PubMed:20172860).; [Uromodulin, secreted form]: Secreted. Detected in urine.