Uncx Antibodies

AND Uncx ELISA kits, Uncx Proteins

Many biological assays use antibodies to detect Uncx, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Uncx in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Uncx antibodies...

We validate the specificity of these antibodies to Uncx by testing them on tissues known to express Uncx positively and negatively. Browse below to find the Uncx antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Uncx Infographic by Boster Bio

All Uncx Products

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Specificity

Applications

Price

Anti-UNCX Antibody (C-term)

Immunofluorescent analysis of U251 cells, using UNCX Antibody (C-term)

Human

IF, WB

$299
Cat # A14476
80 µl

UNCX (NM_001080461) Human Over-expression Lysate

Human

$960
Cat # LS340260
20 µg, 100 µg

Uncx Overview

Facts about Homeobox protein unc-4 homolog.

Homeobox protein unc-4 homolog (Uncx)

Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton.

May act upstream of PAX9. Plays a role in controlling the evolution of connections of hypothalamic neurons to pituitary elements, enabling central neurons to reach the peripheral blood circulation and to deliver hormones for management of peripheral functions.

Gene Information

Mouse
Gene Name:	Uncx
Uniprot:	O08934
Entrez:	22255

Family

Belongs to:

paired homeobox family

Alternative Names

homeobox protein unc-4 homolog; homeobox protein Uncx4.1; UNC homeobox

Molecular Weight

Mass (kDA):
53.936 kDA

Genomic Context


Mouse

Location:	5 G2\|5 78.75 cM
Sequence:	5;

Tissue Specificity

Expressed in the paraxial mesoderm, in the developing kidney and central nervous system. In the somite, it is restricted to the caudal half of the newly formed somite and sclerotome. In the central nervous system, it is detected in the developing spinal cord, hindbrain, mesencephalon and telencephalon. Expressed in adult and embryonic magnocellular neurons of the hypothalamo-neurohypophysial system.

Diseases

Fracture Of First Cervical Vertebra

Pathways

Cell Proliferation
Notch Signaling Pathway
Somitogenesis
Segmentation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Uncx

References

PMID: 10804169 by Leitges M., et al. The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column.

PMID: 9286595 by Mansouri A., et al. Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system.