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- Table of Contents
USP21 Antibodies
AND USP21 ELISA kits, USP21 Proteins
Many biological assays use antibodies to detect USP21, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP21 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP21 antibodies...
Designing a Western blot for USP21? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the USP21 Western Blot GuideUSP21 Infographic by Boster Bio
All USP21 Products
Product
Figures
Specificity
Applications
Price
Anti-CLDN16/Claudin-16 Antibody Picoband®
2 Citations
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # A06659-1
100 μg/vial
Cat # A06659-1
100 μg/vial
Anti-USP21 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, IF, ICC, WB
$370
Cat # A06639-1
100 μg/vial
Cat # A06639-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06668-2
100 μg/vial
Cat # A06668-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06678-2
100 μg/vial
Cat # A06678-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06663
100 μg/vial
Cat # A06663
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, ICC, WB
$370
Cat # A06693-1
100 µg/vial
Cat # A06693-1
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, ICC, WB
$370
Cat # A06189-1
100 μg/vial
Cat # A06189-1
100 μg/vial
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A06660-1
100 µg/vial
Cat # A06660-1
100 µg/vial
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06656-3
100 μg/vial
Cat # A06656-3
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A06182-1
100 μg/vial
Cat # A06182-1
100 μg/vial
Human, Monkey, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A06657-2
100 μg/vial
Cat # A06657-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A06655-1
100 μg/vial
Cat # A06655-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A06193-1
100 μg/vial
Cat # A06193-1
100 μg/vial
USP21 Overview
Facts about Ubiquitin carboxyl-terminal hydrolase 21.
Ubiquitin carboxyl-terminal hydrolase 21 (USP21)
Deubiquitinates histone H2A, a particular tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of both di- and trimethylation of histone H3 in'Lys-4', resulting in regulation of transcriptional initiation.
Regulates gene expression through histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no impact on Sentrin-1 conjugates (PubMed:10799498).
Gene Information
| Human | |
|---|---|
| Gene Name: | USP21 |
| Uniprot: | Q9UK80 |
| Entrez: | 27005 |
Family
| Belongs to: |
|---|
| peptidase C19 family |
Alternative Names
Deubiquitinating enzyme 21; EC 3.1.2.15; EC 3.4.19.12; MGC3394; ubiquitin carboxyl-terminal hydrolase 21; ubiquitin specific peptidase 21; ubiquitin specific protease 21; ubiquitin thioesterase 21; Ubiquitin thiolesterase 21; ubiquitin-specific processing protease 21; ubiquitin-specific protease 16; Ubiquitin-specific-processing protease 21; USP16; USP23NEDD8-specific protease
Molecular Weight
Mass (kDA):
62.656 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q23.3 |
| Sequence: | 1; NC_000001.11 (161159487..161165752) |
Tissue Specificity
Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Insulin Resistance
- Diabetes Mellitus, Non-insulin-dependent
- Diabetes Mellitus
- Hypokinesia
Interacting Proteins
- KRT40
Pathways
- Localization
- Methylation
- Regeneration
- Insulin Secretion
- Cell Growth
- Histone Modification
- Regulation Of Cell Growth
- Nuclear Export
PTMs
- Methylation
- Ubiquitination
- Phosphorylation
Research Areas
- Cell Biology
- Neuroscience
- Ubiquitin Proteasome Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USP21
bosterbio.com/bosterbio-gene-info-cards/USP21
References
PMID: 10786635 by Smith T.S., et al. Sequencing, tissue distribution and chromosomal assignment of a novel ubiquitin-specific protease USP23.
PMID: 10799498 by Gong L., et al. Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins.
1 Publications of Boster USP21 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.jff.2021.104661, Genetically encoded probiotic EcN 1917 alleviates alcohol-induced acute liver in...
*More publications can be found for each product on its corresponding product page