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- Table of Contents
Facts about Ubiquitin carboxyl-terminal hydrolase 49.
Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons. .
Human | |
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Gene Name: | USP49 |
Uniprot: | Q70CQ1 |
Entrez: | 25862 |
Belongs to: |
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peptidase C19 family |
Deubiquitinating enzyme 49; EC 3.1.2.15; EC 3.4.19.12; MGC20741; ubiquitin carboxyl-terminal hydrolase 49; ubiquitin specific peptidase 49; ubiquitin specific protease 49; ubiquitin thioesterase 49; Ubiquitin thiolesterase 49; Ubiquitin-specific-processing protease 49
Mass (kDA):
79.198 kDA
Human | |
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Location: | 6p21.1 |
Sequence: | 6; NC_000006.12 (41789896..41895375, complement) |
Nucleus.
PMID: 14715245 by Quesada V., et al. Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.
PMID: 23824326 by Zhang Z., et al. USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.