Pantetheinase Antibodies

AND VNN1 ELISA kits, Pantetheinase Proteins

Many biological assays use antibodies to detect Pantetheinase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pantetheinase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pantetheinase antibodies...

We validate the specificity of these antibodies to Pantetheinase by testing them on tissues known to express VNN1 positively and negatively. Browse below to find the VNN1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Pantetheinase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the VNN1 Western Blot Guide

VNN1 Infographic by Boster Bio

All VNN1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-VNN1 Antibody Picoband®

Western blot analysis of VNN1 using anti-VNN1 antibody (PB10106)

Human

$370
Cat # PB10106
100 μg/vial

VNN1 (NM_004666) Human Over-expression Lysate

Human

$960
Cat # LS008876
20 µg, 100 µg

VNN1 Overview

Facts about Pantetheinase.

VNN1 3D structure. Source: alphafold

Pantetheinase (VNN1)

Amidohydrolase that hydrolyzes specifically among those carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. .

Gene Information

Human
Gene Name:	VNN1
Uniprot:	O95497
Entrez:	8876

Family

Belongs to:

carbon-nitrogen hydrolase superfamily

Alternative Names

EC 3.5.1; EC 3.5.1.92; HDLCQ8; MGC116930; MGC116931; MGC116932; Pantetheinase; Pantetheine hydrolase; Tiff66; Tiff66MGC116933; vanin 1; Vanin1; Vanin-1; vannin 1; Vascular non-inflammatory molecule 1; VNN1

Molecular Weight

Mass (kDA):
57.012 kDA

Genomic Context


Human

Location:	6q23.2
Sequence:	6; NC_000006.12 (132680849..132714055, complement)

Tissue Specificity

Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

Diseases

Malignant Neoplasms
Inflammation
Cardiovascular Diseases
Malaria
Parasitemia
Colorectal Cancer
Colorectal Neoplasms
Candidiasis
Communicable Diseases
Inflammatory Response
Carcinogenesis
Leukemia, Myelocytic, Acute
Fibrosis

Myeloid Leukemia
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Purpura, Thrombocytopenic, Idiopathic
Infective Disorder
Neointima
Steatohepatitis

Pathways

Lymphocyte Migration
Transport
Cell Activation
Cell Cycle
Ovulation
Pathogenesis
Inflammatory Response

Transdifferentiation

PTMs

Carboxylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VNN1

References

PMID: 9790769 by Galland F., et al. Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6.

PMID: 10567687 by Maras B., et al. Is pantetheinase the actual identity of mouse and human vanin-1 proteins?