V-set and transmembrane domain-containing protein 5 (Vstm5)

Mobile adhesion-like membrane protein of the central nervous system (CNS) which modulates both the position and sophistication of central neurons by altering their membrane morphology and dynamics. Involved in the formation of neuronal dendrites and protrusions such as dendritic filopodia.

In synaptogenesis, regulates synapse formation by altering dendritic spine morphology and actin distribution. Promotes formation of unstable neuronal spines like thin and branched types.