WARS1 Antibodies

AND WARS1 ELISA kits, WARS1 Proteins

Many biological assays use antibodies to detect WARS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WARS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WARS1 antibodies...

We validate the specificity of these antibodies to WARS1 by testing them on tissues known to express WARS1 positively and negatively. Browse below to find the WARS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WARS1 Infographic by Boster Bio

All WARS1 Products

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Product

Figures

Specificity

Applications

Price

Human WARS Recombinant Protein

SDS-PAGE

$250
Cat # PROTP23381
Starting from 20ug

Tryptophanyl tRNA synthetase (WARS) (NM_004184) Human Over-expression Lysate

Tryptophanyl tRNA synthetase (WARS) Human Over-expression Lysates NM_004184

Human

$628
Cat # LS007453
20 µg, 100 µg

Anti-WRS/WARS1 Antibody Picoband®

Western blot analysis of WRS/WARS1 using anti-WRS/WARS1 antibody (A02444-2)

IHC analysis of WRS/WARS1 using anti-WRS/WARS1 antibody (A02444-2)

Human, Mouse

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02444-2
100 µg/vial

WARS1 Overview

Facts about Tryptophan--tRNA ligase, cytoplasmic.

WARS1 3D structure. Source: alphafold

Tryptophan--tRNA ligase, cytoplasmic (WARS1)

Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it.

T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.

Gene Information

Human
Gene Name:	WARS1
Uniprot:	P23381
Entrez:	7453

Family

Belongs to:

class-I aminoacyl-tRNA synthetase family

Alternative Names

Tryptophan--tRNA ligase, cytoplasmic

Molecular Weight

Mass (kDA):
53.165 kDA

Genomic Context


Human

Location:	14q32.2
Sequence:	14; NC_000014.9 (100333789..100376327, complement)

Subcellular Localizations

Cytoplasm.

Interacting Proteins

CDH5
TERF1

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WARS1

References

PMID: 1761529 by Rubin B.Y., et al. Interferon induces tryptophanyl-tRNA synthetase expression in human fibroblasts.

PMID: 1763065 by Fleckner J., et al. Human interferon gamma potently induces the synthesis of a 55-kDa protein (gamma 2) highly homologous to rabbit peptide chain release factor and bovine tryptophanyl-tRNA synthetase.