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Protein Wnt-7a Antibodies
AND WNT7A ELISA kits, Protein Wnt-7a Proteins
Many biological assays use antibodies to detect Protein Wnt-7a, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Wnt-7a in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Wnt-7a antibodies...
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WNT7A Infographic by Boster Bio
All WNT7A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # RP1088
100 μg/vial
Cat # RP1088
100 μg/vial
WNT7A Overview
Facts about Protein Wnt-7a.
Protein Wnt-7a (WNT7A)
Ligand for members of the frizzled family of seven transmembrane receptors which functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an essential role in embryonic development, such as dorsal versus ventral patterning during limb development, skeleton growth and urogenital tract development (PubMed:16826533).
Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (PubMed:30026314). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes (By similarity).
Gene Information
| Human | |
|---|---|
| Gene Name: | WNT7A |
| Uniprot: | O00755 |
| Entrez: | 7476 |
Family
| Belongs to: |
|---|
| Wnt family |
Alternative Names
protein Wnt-7a; proto-oncogene Wnt7a protein; wingless-type MMTV integration site family, member 7A; Wnt7a; Wnt-7a
Molecular Weight
Mass (kDA):
39.005 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.1 |
| Sequence: | 3; NC_000003.12 (13816258..13880071, complement) |
Tissue Specificity
Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix. Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Endometrial Polyp
- Cell Transformation, Neoplastic
- Carcinoma
- Tissue Adhesions
- Limb Deformities, Congenital
- Malignant Neoplasm Of Lung
- Cell Invasion
- Neoplasm Metastasis
- Lung Neoplasms
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- Reck
- WIF1
Pathways
- Limb Development
- Cell Proliferation
- Localization
- Cell Growth
- Regeneration
- Pathogenesis
- Cell Adhesion
- Methylation
- Cell Differentiation
- Glycosylation
- Wound Healing
- Oncogenesis
- Cell-cell Adhesion
PTMs
- Methylation
- Phosphorylation
- Glycosylation
Research Areas
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WNT7A
bosterbio.com/bosterbio-gene-info-cards/WNT7A
References
PMID: 9161407 by Bui T.D., et al. Isolation of a full-length human WNT7A gene implicated in limb development and cell transformation, and mapping to chromosome 3p25.
PMID: 8893824 by Ikegawa S., et al. Isolation, characterization and chromosomal assignment of the human WNT7A gene.
1 Publications of Boster Protein Wnt-7a Antibodies & ELISA Kits
- PubMed ID: 33359712, An R,Wang X,Yang L,Zhang J,Wang N,Xu F,Hou Y,Zhang H,Zhang L. Polystyrene microp...
*More publications can be found for each product on its corresponding product page