Recombinant Human FGF10 Protein

The Fibroblast Growth Factors (FGFs) are heparin binding glycoproteins that exert a variety of biological activities toward cells of mesenchymal, neuronal, and epithelial origin. FGF-10 belongs to the subgroup of FGFs that also includes FGF-3, -7, and -22 (1). Mature human FGF-10 is an approximately 20 kDa protein that contains a serine-rich region near its N-terminus FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes,including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity ofFGF7. Studiesof the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of limb bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

Product Info Summary

SKU: R01709
Size: 100μg/vial
Origin Species: Human
Source: E. coli Gln38-Ser208

Product Name

Recombinant Human FGF10 Protein

See all FGF-10 products

SKU/Catalog Number

R01709

Size

100μg/vial

Form

Lyophilized

Description

The Fibroblast Growth Factors (FGFs) are heparin binding glycoproteins that exert a variety of biological activities toward cells of mesenchymal, neuronal, and epithelial origin. FGF-10 belongs to the subgroup of FGFs that also includes FGF-3, -7, and -22 (1). Mature human FGF-10 is an approximately 20 kDa protein that contains a serine-rich region near its N-terminus FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes,including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity ofFGF7. Studiesof the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of limb bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

Storage & Handling

Lyophilized recombinant human KGF-2/FGF10 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, KGF-2/FGF10 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

Cite This Product

Recombinant Human FGF10 Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # R01709)

Formulation

Lyophilized after extensive dialysis against PBS.

Predicted MW

23.436kDa

Endotoxin

Reconstitute in ddH2O at 100 μg/mL.

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Validation Images & Assay Conditions

Gene/Protein Information For FGF10 (Source: Uniprot.Org, NCBI)

Uniprot ID

O15520

Gene ID

2255

Gene Name

FGF10

Full Name

Fibroblast growth factor 10

Weight

23.436kDa

Superfamily

heparin-binding growth factors family

Alternative Names

FGF10; FGF-10; fibroblast growth factor 10; Keratinocyte growth factor 2; KGF2; KGF-2; produced by fibroblasts of urinary bladder lamina propria FGF10 fibroblast growth factor 10 fibroblast growth factor 10|FGF-10|keratinocyte growth factor 2|produced by fibroblasts of urinary bladder lamina propria

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on FGF10, check out the FGF10 Infographic

FGF10 infographic

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In this infographic you will see the following information for FGF10: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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