Product Info Summary
SKU: | A00335 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | IF, IHC, ICC, WB |
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Product info
Product Name
Anti-Insulin-like growth factor II IGF2 Antibody
View all IGF-II/IGF2 Antibodies
SKU/Catalog Number
A00335
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Insulin-like growth factor II IGF2 Antibody catalog # A00335. Tested in WB,ICC/IF,IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Insulin-like growth factor II IGF2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00335)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Caspase-3 around the phosphorylation site of S150.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00335 is reactive to IGF2 in Human
Applications
A00335 is guaranteed for IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
20.14kDa
Background of IGF-II/IGF2
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Patricia Giraldo, Nucleic Acids Res., Nov 2003; 31: 6290 - 6305.
R Halaban, J. Cell Biol., Aug 1983; 97: 480.
Hee-Young Park, J. Biol. Chem., Jun 1999; 274: 16470.
BB Fuller, J. Biol. Chem., Mar 1987; 262: 4024 - 4033.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:1,000
ICC: 1:100-1:500
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunocytochemistry staining of IGF2 using Anti-Insulin-like growth factor II IGF2 Antibody (A00335).
ICC staining IGF2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 1. Western blotting validation for Anti-Insulin-like growth factor II IGF2 Antibody A00335
Western blot analysis of IGF2 on human placenta lysates using anti-IGF2 antibody at 1/1Protein Target Info & Infographic
Gene/Protein Information For IGF2 (Source: Uniprot.org, NCBI)
Gene Name
IGF2
Full Name
Insulin-like growth factor II
Weight
20.14kDa
Superfamily
insulin family
Alternative Names
C11orf43; chromosome 11 open reading frame 43; FLJ22066; FLJ44734; GRDF; IGF2; IGF-2; IGFII; IGF-II; insulin-like growth factor 2 (somatomedin A); insulin-like growth factor II; insulin-like growth factor type 2; MSA; PEG2; PP9974; somatomedin-A IGF2 C11orf43, GRDF, IGF-II, PP9974, SRS3 insulin like growth factor 2 insulin-like growth factor II|T3M-11-derived growth factor|insulin-like growth factor 2 (somatomedin A)|insulin-like growth factor type 2|preptin
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on IGF2, check out the IGF2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for IGF2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Insulin-like growth factor II IGF2 Antibody (A00335)
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No publications found for A00335
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