Product Info Summary
SKU: | A00385 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Protein capicua homolog CIC Antibody
SKU/Catalog Number
A00385
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Protein capicua homolog CIC Antibody catalog # A00385. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Protein capicua homolog CIC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00385)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Survivin around the phosphorylation site of T34.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Does not cross-react with eNOS or nNOS.
Reactive Species
A00385 is reactive to CIC in Human, Mouse, Rat
Applications
A00385 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
163.82kDa
Background of Capicua
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
David A. Jans, J. Biol. Chem., Nov 1996; 271: 30781.
Eugene Estella, Diabetes, Aug 2006; 55: 2212 - 2219.
Yong Gu, J. Biol. Chem., May 1996; 271: 10816.
Jiuru Sun, J. Biol. Chem., Nov 1996; 271: 27802.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CIC (Source: Uniprot.org, NCBI)
Gene Name
CIC
Full Name
Protein capicua homolog
Weight
163.82kDa
Alternative Names
capicua homolog (Drosophila); KIAA0306capicua (Drosophila) homolog; protein capicua homolog CIC MRD45 capicua transcriptional repressor protein capicua homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CIC, check out the CIC Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CIC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Protein capicua homolog CIC Antibody (A00385)
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No publications found for A00385
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