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- Table of Contents
Proto-oncogene vav Antibodies
AND VAV1 ELISA kits, Proto-oncogene vav Proteins
Many biological assays use antibodies to detect Proto-oncogene vav, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proto-oncogene vav in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proto-oncogene vav antibodies...
Designing a Western blot for Proto-oncogene vav? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the VAV1 Western Blot GuideVAV1 Infographic by Boster Bio
All VAV1 Products
Product
Figures
Specificity
Applications
Price
Human
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M00691-1
100 μl/vial
Cat # M00691-1
100 μl/vial
Human, Mouse, Rat
ELISA
$540
Cat # EKC2009
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2009
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1589
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1589
1 kit, containing one 96-well plate and all necessary reagents
VAV1 Overview
Facts about Proto-oncogene vav.
Proto-oncogene vav (VAV1)
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus resulting in cell differentiation and/or proliferation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | VAV1 |
| Uniprot: | P15498 |
| Entrez: | 7409 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
oncogene vav; proto-oncogene vav; vav 1 guanine nucleotide exchange factor; vav proto-oncogene; Vav1; Vav-1; vav-T; VAVvav 1 oncogene
Molecular Weight
Mass (kDA):
98.314 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (6772708..6857366) |
Tissue Specificity
Widely expressed in hematopoietic cells but not in other cell types.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Leukemia
- Cell Transformation, Neoplastic
- Lymphoma
- Immunologic Deficiency Syndromes
- Autoimmune Reaction
- Inflammation
- Autoimmunity
- Neoplasm Metastasis
- Acute Promyelocytic Leukemia
- Carcinoma
Interacting Proteins
- ABI1
- ABL1
- GAB1
- GRB2
- KHDRBS1
- LCP2
- RAC1
- SH3BP2
- ZNF655
Pathways
- Cell Activation
- T Cell Activation
- Localization
- Cell Proliferation
- Cell Development
- Cell Adhesion
- Cytokine Production
- Secretion
- Phagocytosis
- Cell Cycle
- Lymphocyte Activation
- Immune Response
- Cell Differentiation
PTMs
- Phosphorylation
- Dephosphorylation
- Methylation
- Cleavage
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VAV1
bosterbio.com/bosterbio-gene-info-cards/VAV1
References
PMID: 2069873 by Coppola J., et al. Mechanism of activation of the vav protooncogene.
PMID: 10760587 by Denkinger D.J., et al. Genomic organization and regulation of the vav proto-oncogene.