This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial.
Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid.
Mouse | |
---|---|
Gene Name: | Aadat |
Uniprot: | Q9WVM8 |
Entrez: | 23923 |
Belongs to: |
---|
class-I pyridoxal-phosphate-dependent aminotransferase family |
AADAT; alphaAminoadipate Aminotransferase; alpha-Aminoadipate Aminotransferase; aminoadipate aminotransferase; EC 2.6.1.39,2-aminoadipate aminotransferase; EC 2.6.1.7,2-aminoadipate transaminase; KAT/AadAT; KAT2; KAT2mitochondrial; Kynurenine aminotransferase II; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase II; L kynurenine/alpha aminoadipate aminotransferase
Mass (kDA):
47.598 kDA
Mouse | |
---|---|
Location: | 8 B3.1|8 30.85 cM |
Sequence: | 8; |
Expressed mainly in kidney and to a lesser amount in liver and brain.
PMID: 10441733 by Yu P., et al. Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease.