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- Table of Contents
Designing an IHC experiment for Aadat? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the AADAT IHC GuideFacts about Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial.
Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid.
| Mouse | |
|---|---|
| Gene Name: | Aadat |
| Uniprot: | Q9WVM8 |
| Entrez: | 23923 |

| Belongs to: |
|---|
| class-I pyridoxal-phosphate-dependent aminotransferase family |

AADAT; alphaAminoadipate Aminotransferase; alpha-Aminoadipate Aminotransferase; aminoadipate aminotransferase; EC 2.6.1.39,2-aminoadipate aminotransferase; EC 2.6.1.7,2-aminoadipate transaminase; KAT/AadAT; KAT2; KAT2mitochondrial; Kynurenine aminotransferase II; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase II; L kynurenine/alpha aminoadipate aminotransferase
Mass (kDA):
47.598 kDA

| Mouse | |
|---|---|
| Location: | 8 B3.1|8 30.85 cM |
| Sequence: | 8; |
Expressed mainly in kidney and to a lesser amount in liver and brain.




PMID: 10441733 by Yu P., et al. Genomic organization and expression analysis of mouse kynurenine aminotransferase II, a possible factor in the pathophysiology of Huntington's disease.