Many biological assays use antibodies to detect KEL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KEL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KEL antibodies...
We validate the specificity of these antibodies to KEL by testing them on tissues known to express KEL positively and negatively. Browse below to find the KEL antibody that suites your experiment. We have 85 of these antibodies and many publications and validation images.
If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.
Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.
.
Gene Information
Human
Gene Name:
KEL
Uniprot:
P23276
Entrez:
3792
Family
Belongs to:
peptidase M13 family
Alternative Names
CD238 antigen; CD238; EC 3.4.24.-; ECE3; KEL; kell blood group antigen; kell blood group glycoprotein; Kell blood group; Kell blood group, metalloendopeptidase; Kell blood group, metallo-endopeptidase; Kell
Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow.
Subcellular Localizations
Cell membrane; Single-pass type II membrane protein. Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.
Diseases
Rheumatic Heart Disease
Asthma
Hemolytic Disorder
Kidney Failure
Kidney Diseases
Neoplasms
Malignant Neoplasms
Erythroblastosis, Fetal
Depressive Disorder
Sterility
Alloimmunization
Bacterial Infections
Pain
Bulla
Infective Disorder
Transfusion Reaction
Hypertensive Disease
Tuberculosis
Tissue Adhesions
Abscess
Pathways
Excretion
Transport
Localization
Oogenesis
Proteolysis
Immune Response
Oocyte Maturation
Glomerular Filtration
Demethylation
Bilirubin Transport
Renal Tubular Secretion
Complement Activation
Cytokinesis
Cell Division
Menstruation
Antigenic Variation
Translation
Mrna Transcription
Water Transport
Glucose Transport
PTMs
Phosphorylation
Hydroxylation
Cleavage
Sulphation
Biotinylation
For details, visit: bosterbio.com/bosterbio-gene-info-cards/KEL
References
PMID: 1712490 by Lee S., et al. Molecular cloning and primary structure of Kell blood group protein.
PMID: 7858266 by Lee S., et al. Organization of the gene encoding the human Kell blood group protein.
7 Publications of Boster KEL Antibodies & ELISA Kits
PubMed ID: 10.1039/C6RA14831J, Individual and combined antioxidant effects of ginsenoside F2 and cyanidin-3-O-g...