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- Table of Contents
ABCD3 Antibodies
AND ABCD3 ELISA kits, ABCD3 Proteins
Many biological assays use antibodies to detect ABCD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ABCD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ABCD3 antibodies...
Designing a Western blot for ABCD3? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ABCD3 Western Blot GuideABCD3 Infographic by Boster Bio
All ABCD3 Products
Product
Figures
Specificity
Applications
Price
Anti-PMP70/ABCD3 Antibody Picoband®
1 Citations
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PA2091
100 μg/vial
Cat # PA2091
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # M02370
100 μl
Cat # M02370
100 μl
Mouse
ELISA
$499
Cat # FEK0357
96 wells/kit, with removable strips.
Cat # FEK0357
96 wells/kit, with removable strips.
ABCD3 Overview
Facts about ATP-binding cassette sub-family D member 3.
ATP-binding cassette sub-family D member 3 (ABCD3)
Probable transporter involved in the transportation of branched-chain fatty acids and C27 bile acids into the peroxisome; the latter purpose is a crucial step in bile acid biosynthesis (PubMed:25168382). The nucleotide-binding fold functions as an ATP- binding subunit with ATPase activity (PubMed:11248239).
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Gene Information
| Human | |
|---|---|
| Gene Name: | ABCD3 |
| Uniprot: | P28288 |
| Entrez: | 5825 |
Family
| Belongs to: |
|---|
| ABC transporter superfamily |
Alternative Names
70 kDa peroxisomal membrane protein; ABC43; ATP-binding cassette, sub-family D (ALD), member 3; peroxisomal membrane protein 1 (70kD, Zellweger syndrome); Peroxisomal membrane protein-1 (70kD); PMP70ATP-binding cassette sub-family D member 3; PXMP1dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); ZWS2
Molecular Weight
Mass (kDA):
75.476 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p21.3 |
| Sequence: | 1; NC_000001.11 (94418086..94518663) |
Subcellular Localizations
Peroxisome membrane; Multi-pass membrane protein.
Diseases
- Adrenoleukodystrophy
- Zellweger Syndrome
- Neurodegenerative Disorders
- Peroxisomal Disorders
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Nervousness
- Demyelination
- Demyelinating Diseases
- Liver Carcinoma
- Glioma
Interacting Proteins
- ABCD1
- PEX19
Pathways
- Transport
- Localization
- Pathogenesis
- Fatty Acid Beta-oxidation
- Translation
- Membrane Biogenesis
- Protein Import
- Fatty Acid Oxidation
- Rna Interference
- Protein Targeting
- Fatty Acid Elongation
- Brain Development
- Proteolysis
PTMs
- Oxidation
- Phosphorylation
Research Areas
- ABC Transporters
- Cellular Markers
- Lipid and Metabolism
- Neuroscience
- Peroxisome Markers
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ABCD3
bosterbio.com/bosterbio-gene-info-cards/ABCD3
References
PMID: 1301993 by Gaertner J., et al. Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome.
PMID: 1536884 by Kamijo K., et al. Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a member of ATP-binding cassette transporters.