Anti-PMP70/ABCD3 Antibody

PMP70 antibody

Boster Bio Anti-PMP70/ABCD3 Antibody catalog # PA2091. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA2091
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

Product Name

Anti-PMP70/ABCD3 Antibody

View all PMP70 Antibodies

SKU/Catalog Number

PA2091

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-PMP70/ABCD3 Antibody catalog # PA2091. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-PMP70/ABCD3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2091)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human PMP70, different from the related mouse and rat sequences by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA2091 is reactive to ABCD3 in Human, Mouse, Rat

Applications

PA2091 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

75.476kDa

Background of PMP70

ATP-binding cassette sub-family D member 3 is a protein that in humans is encoded by the ABCD3 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The gene was assigned to human chromosome 1p21-p22 by in situ hybridization. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Rat, Human, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For ABCD3 (Source: Uniprot.org, NCBI)

Gene Name

ABCD3

Full Name

ATP-binding cassette sub-family D member 3

Weight

75.476kDa

Superfamily

ABC transporter superfamily

Alternative Names

70 kDa peroxisomal membrane protein; ABC43; ATP-binding cassette, sub-family D (ALD), member 3; peroxisomal membrane protein 1 (70kD, Zellweger syndrome); Peroxisomal membrane protein-1 (70kD); PMP70ATP-binding cassette sub-family D member 3; PXMP1dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)); ZWS2 ABCD3 ABC43, CBAS5, PMP70, PXMP1, ZWS2 ATP binding cassette subfamily D member 3 ATP-binding cassette sub-family D member 3|70 kDa peroxisomal membrane protein|ATP-binding cassette, sub-family D (ALD), member 3|Peroxisomal membrane protein-1 (70kD)|dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1))|peroxisomal membrane protein 1 (70kD, Zellweger syndrome)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on ABCD3, check out the ABCD3 Infographic

ABCD3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for ABCD3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-PMP70/ABCD3 Antibody

Question

We appreciate helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for brain lung using anti-PMP70/ABCD3 antibody PA2091. Let me know if you need anything else.

M. Collins

Verified customer

Asked: 2019-12-31

Answer

We appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-12-31

Question

Is this PA2091 anti-PMP70/ABCD3 antibody reactive to the isotypes of ABCD3?

Verified Customer

Verified customer

Asked: 2019-09-27

Answer

The immunogen of PA2091 anti-PMP70/ABCD3 antibody is A synthetic peptide corresponding to a sequence at the C-terminus of human PMP70(646-659aa EFKQITEDTVEFGS), different from the related mouse and rat sequences by one amino acid. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2019-09-27

Question

We are currently using anti-PMP70/ABCD3 antibody PA2091 for human tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on pig tissues as well?

R. Krishna

Verified customer

Asked: 2018-02-14

Answer

The anti-PMP70/ABCD3 antibody (PA2091) has not been validated for cross reactivity specifically with pig tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2018-02-14

Size

Conjugation

Total: $370

SKU:PA2091

In stock, 1 left.

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PA2091
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

$50 fee for conjugation. Antibody size is reduced to 50ug.

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