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- Table of Contents
Facts about Alkaline ceramidase 2.
Inhibits the maturation of protein glycosylation in the Golgi complex, such as that of integrin beta-1 (ITGB1) and of LAMP1, by increasing the levels of sphingosine. Inhibits cell adhesion by decreasing the degree of ITGB1 in the cell surface.
Mouse | |
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Gene Name: | Acer2 |
Uniprot: | Q8VD53 |
Entrez: | 230379 |
Belongs to: |
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alkaline ceramidase family |
Alkaline ceramidase 2
Mass (kDA):
31.369 kDA
Mouse | |
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Location: | 4|4 C4 |
Sequence: | 4; |
PMID: 11420682 by Graveel C.R., et al. Expression profiling and identification of novel genes in hepatocellular carcinomas.
PMID: 16940153 by Xu R., et al. Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P.