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Actin-related protein 2 Antibodies
AND ACTR2 ELISA kits, Actin-related protein 2 Proteins
Many biological assays use antibodies to detect Actin-related protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Actin-related protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Actin-related protein 2 antibodies...
Designing a Western blot for Actin-related protein 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACTR2 Western Blot GuideACTR2 Infographic by Boster Bio
All ACTR2 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03898-1
100 μg/vial
Cat # A03898-1
100 μg/vial
ACTR2 Overview
Facts about Actin-related protein 2.
Actin-related protein 2 (ACTR2)
ATP-binding part of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the power for cell motility (PubMed:9000076).
Seems to contact the pointed end of the daughter actin filament (PubMed:9000076). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947).
Gene Information
| Human | |
|---|---|
| Gene Name: | ACTR2 |
| Uniprot: | P61160 |
| Entrez: | 10097 |
Family
| Belongs to: |
|---|
| actin family |
Alternative Names
actin-related protein 2; ARP2 (actin-related protein 2, yeast) homolog; ARP2 actin-related protein 2 homolog (yeast); ARP2Actin-like protein 2
Molecular Weight
Mass (kDA):
44.761 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p14 |
| Sequence: | 2; NC_000002.12 (65227695..65271253) |
Subcellular Localizations
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Diseases
- Wiskott-aldrich Syndrome
- Tissue Adhesions
- Protrusion
- Shigella Infections
- Spinocerebellar Ataxia, Autosomal Recessive 1
- Vaccinia
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Immunologic Deficiency Syndromes
- Dysplasia
- Infective Disorder
- Melanoma
Pathways
- Actin Nucleation
- Localization
- Cell Motility
- Endocytosis
- Locomotion
- Cell Migration
- Transport
- Rna Interference
- Pathogenesis
- Chemotaxis
- Phagocytosis
- Clathrin-mediated Endocytosis
- Receptor-mediated Endocytosis
PTMs
- Phosphorylation
- Dephosphorylation
- Prenylation
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTR2
bosterbio.com/bosterbio-gene-info-cards/ACTR2
References
PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
PMID: 9000076 by Welch M.D., et al. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.