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Actin-related protein 2 Antibodies
AND ACTR2 ELISA kits, Actin-related protein 2 Proteins
Many biological assays use antibodies to detect Actin-related protein 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Actin-related protein 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Actin-related protein 2 antibodies...
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ACTR2 Infographic by Boster Bio
All ACTR2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$405
Cat # A03898
100ul
Cat # A03898
100ul
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03898-1
100 μg/vial
Cat # A03898-1
100 μg/vial
ACTR2 Overview
Facts about Actin-related protein 2.
Actin-related protein 2 (ACTR2)
ATP-binding part of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9000076). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the power for cell motility (PubMed:9000076).
Seems to contact the pointed end of the daughter actin filament (PubMed:9000076). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947).
Gene Information
| Human | |
|---|---|
| Gene Name: | ACTR2 |
| Uniprot: | P61160 |
| Entrez: | 10097 |
Family
| Belongs to: |
|---|
| actin family |
Alternative Names
actin-related protein 2; ARP2 (actin-related protein 2, yeast) homolog; ARP2 actin-related protein 2 homolog (yeast); ARP2Actin-like protein 2
Molecular Weight
Mass (kDA):
44.761 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p14 |
| Sequence: | 2; NC_000002.12 (65227695..65271253) |
Subcellular Localizations
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Diseases
- Wiskott-aldrich Syndrome
- Tissue Adhesions
- Protrusion
- Shigella Infections
- Spinocerebellar Ataxia, Autosomal Recessive 1
- Vaccinia
- Malignant Neoplasms
- Neoplasms
- Cell Invasion
- Immunologic Deficiency Syndromes
- Dysplasia
- Infective Disorder
- Melanoma
Pathways
- Actin Nucleation
- Localization
- Cell Motility
- Endocytosis
- Locomotion
- Cell Migration
- Transport
- Rna Interference
- Pathogenesis
- Chemotaxis
- Phagocytosis
- Clathrin-mediated Endocytosis
- Receptor-mediated Endocytosis
PTMs
- Phosphorylation
- Dephosphorylation
- Prenylation
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTR2
bosterbio.com/bosterbio-gene-info-cards/ACTR2
References
PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
PMID: 9000076 by Welch M.D., et al. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.