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- Table of Contents
Facts about Actin-related protein 2.
Seems to contact the pointed end of the daughter actin filament (PubMed:9000076). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:17220302, PubMed:29925947).
Human | |
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Gene Name: | ACTR2 |
Uniprot: | P61160 |
Entrez: | 10097 |
Belongs to: |
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actin family |
actin-related protein 2; ARP2 (actin-related protein 2, yeast) homolog; ARP2 actin-related protein 2 homolog (yeast); ARP2Actin-like protein 2
Mass (kDA):
44.761 kDA
Human | |
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Location: | 2p14 |
Sequence: | 2; NC_000002.12 (65227695..65271253) |
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Are you looking for a monoclonal antibody in rat that recognizes ACTR2? Boster Bio offers a variety anti ACTR2 antibody options. This product reacts with Rats, Monkeys, and Mice. Read on to discover how to use these rat monoclonal antibodies in your research. Here are a few examples of the many ways you can use these antibodies.
The ACTR2Marker is an ARP family member that contains a lipidbinding domain that facilitates attachment to membranes. ACTR2 is a class of ARP members that exhibits a protein folding pattern very similar to that of actin. It is one of three components of the seven-protein complex Arp2/3. The Human Protein Atlas project has produced Prestige Antibodies. It supports some of most detailed industry characterization.
When analyzed by RNA-seq, the ACTR2 marker is correlated with the expression of Arp2/3 subunits in pan-cancers and healthy tissues. This gene expression can also be associated with the development and spread of various types cancers, including non-small cell lung cancer. However, ACTR2 & ARPC2 don't correlate with tumor purity. The ACTR2 marker has a correlation with cellular proliferation, but not with tumor invasiveness.
Contact Sanbio to learn more about ACTR3, a gene involved in ciliogenesis. We're happy to answer any questions that you may have and help you start your search for information about ACTR3. Boster offers information on a range of genes including ACTR3, along with helpful tips and tricks for getting the most out it.
Boster has the right product for you, whether you need a primary antibody to detect ACTR3 and a recombinant proteins. Boster provides high-affinity antibodies, which have been extensively validated across a variety of research techniques, including Western Blotting, Immunohistochemistry, and ELISA. Boster will deliver high-quality and reliable recombinant antibodies.
If you are planning to analyze ACTR4 in cells, there are many options for optimizing your experiment. Boster has provided some excellent optimization tips and guidelines. These tips and guides are listed below. These guides can only be used if the ACTR4 gene is selected as your target. Then optimize the Flow procedure. Boster supplies high-affinity antibodies that are against ACTR4. These antibodies are well-cited and validated on Western Blotting, Immunohistochemistry, and ELISA.
The ELISA assay is the most commonly used method for detecting soluble proteins, and Boster Bio has mastered the art of coating ELISA plates. The ELISA test can detect soluble proteins in their natural state. Boster also offers guidance on sample preparation and ELISA data analysis. A standard curve can be used to obtain more precise data. The standard curves and antibodies are validated using known positive and negative samples so that the results are more reliable.
The candidate gene ACTR2 for detection of lung carcinoma is available. This gene has many functions, including the regulation actin cytoskeleton. It also regulates protein-ubiquitination as well as the progression of different types of tumors. The gene is found in many types and types of cancers, including lung and nonsmall-cell lung cancers. It is closely connected to the WNT and VEGF receptor signaling pathways.
The ACTR2 gene is expressed in the stromal cells of the body, including B cells and T cells. It is expressed in tumor-infiltrating immune cells such as CD4+ T cells, neutrophils, and macrophages. High levels of this gene indicate a poor prognosis in HCC. It is not clear if the gene is linked to the progression or a marker of disease progression.
Boster Bio is your best choice if you're looking for a primary anti-ACTR7 antibody. It offers a wide range of highly cited primary antibodies that have been validated in Western Blotting, Immunohistochemistry, and ELISA. All scientists from all over the world can access Boster products. And, for the most part, they're affordable too! They come in many formats, making it easy to create an experiment that suits your needs.
The ACTR2 gene, a component in the actin complex, is a component. Its expression is controlled by the protein kinase PKR. HCC has poor prognosis when there is high ACTR2 expression and ACTR3. ARPC1A, ARPC2B and ARPC2B are also genes that are associated with ACTR2 gene expression. The ACTR2 gene could be useful in cancer research.
The ACTR2 genes are involved in cancer resistance and progression. It regulates Wnt and MAPK pathways. It also promotes leukocyte transendothelial migration and immune cell infiltration. Further research is necessary to determine the exact mechanism for ACTR2 & ARPC2 function. However, a validation study is required to confirm these findings.
Boster Bio has a commercially available Anti-Actin Related Protein 2 (ACTR2) Antibody. This antibody is tested for specificity in WB, IHC, and IF. This boster bio antibody reacts to human, mouse, and rats cells. It has been thoroughly validated for use with a variety applications and is suitable in a wide range.
The ARP2/3 complex, a family protein found on cells' surfaces, plays a role cell motility and shape. This gene is critical for the assembly de lamellipodial and cell motility. Boster Bio: Best Uses Of The ACTR2 Marker
The ACTR2 marker is an oncogene expressed by tumors. It is thought to play a significant role in the progression, and resistance to treatment. This marker interacts the Arp2/3 actin nucleating component Arp2/3, which is part of the WAVE family. It is also involved in the formation F-actin. There are many uses for the ACTR2 mark, as with many oncogenes.
PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
PMID: 9000076 by Welch M.D., et al. Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.