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- Table of Contents
Designing a Western blot for ADAM9? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ADAM9 Western Blot Guide1 Citations
Facts about Disintegrin and metalloproteinase domain-containing protein 9.
Cleaves and releases a number of molecules with Significant roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5.
May mediate cell-cell, cell- matrix interactions and regulate the motility of cells via interactions with integrins..
| Human | |
|---|---|
| Gene Name: | ADAM9 |
| Uniprot: | Q13443 |
| Entrez: | 8754 |

| Belongs to: |
|---|
| No superfamily |

a disintegrin and metalloproteinase domain 9 (meltrin gamma); ADAM 9; ADAM metallopeptidase domain 9 (meltrin gamma); ADAM metallopeptidase domain 9; ADAM9; Cellular disintegrin-related protein; cone rod dystrophy 9; CORD9; disintegrin and metalloproteinase domain-containing protein 9; EC 3.4.24; EC 3.4.24.-; MCMP; MCMPMDC9KIAA0021Mltng; MDC9; Meltrin gamma; Meltrin-gamma; Metalloprotease/disintegrin/cysteine-rich protein 9; MLTNG; Myeloma cell metalloproteinase
Mass (kDA):
90.556 kDA

| Human | |
|---|---|
| Location: | 8p11.22 |
| Sequence: | 8; NC_000008.11 (38996767..39105261) |
Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart.
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.





PMID: 8647900 by Weskamp G., et al. MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
PMID: 8809033 by McKie N., et al. Cloning of a novel membrane-linked metalloproteinase from human myeloma cells.