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Adipor2 Antibodies
AND Adipor2 ELISA kits, Adipor2 Proteins
Many biological assays use antibodies to detect Adipor2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adipor2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adipor2 antibodies...
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Adipor2 Infographic by Boster Bio
All Adipor2 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS079602
20 µg, 100 µg
Cat # LS079602
20 µg, 100 µg
Adipor2 Overview
Facts about Adiponectin receptor protein 2.
Adiponectin receptor protein 2 (Adipor2)
Receptor for ADIPOQ, an important hormone secreted by adipocytes that modulates glucose and lipid metabolism (PubMed:17327425, PubMed:17068142, PubMed:17268472, PubMed:24742672). Required for normal body fat and glucose homeostasis (PubMed:17327425, PubMed:17068142, PubMed:17268472, PubMed:24742672).
ADIPOQ-binding activates a signaling cascade that leads to greater PPARA action, and finally to increased fatty acid oxidation and glucose uptake (PubMed:12802337, PubMed:17268472, PubMed:24742672). Has intermediate affinity for globular and full-length adiponectin (PubMed:12802337).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Adipor2 |
| Uniprot: | Q8BQS5 |
| Entrez: | 68465 |
Family
| Belongs to: |
|---|
| ADIPOR family |
Alternative Names
ACDCR2; adiponectin receptor 2; adiponectin receptor protein 2; AdipoR2; FLJ21432; PAQR2; PAQR2MGC4640; Progestin and adipoQ receptor family member II
Molecular Weight
Mass (kDA):
43.981 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 6 F1|6 56.78 cM |
| Sequence: | 6; |
Tissue Specificity
Detected in liver and quadriceps muscle (at protein level) (PubMed:17327425). Highly expressed in liver (PubMed:12802337). Highly expressed in white adipose tissue, and at intermediate levels in brown adipose tissue (PubMed:24742672). Expressed at intermediate level in heart, kidney, lung and skeletal muscle. Weakly expressed in brain, spleen and testis.
Diseases
- Obesity
- Insulin Resistance
- Diabetes Mellitus
- Insulin Sensitivity
- Diabetes Mellitus, Non-insulin-dependent
- Malignant Neoplasms
- Inflammation
- Fatty Liver
- Atherosclerosis
- Liver Diseases
- Neoplasms
- Steatohepatitis
- Steatosis
Pathways
- Secretion
- Energy Homeostasis
- Pathogenesis
- Fatty Acid Oxidation
- Cell Proliferation
- Adiponectin Secretion
- Cell Growth
- Gluconeogenesis
- Insulin Secretion
- Rna Interference
- Embryo Development
- Cell Cycle
- Transport
PTMs
- Phosphorylation
- Oxidation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Adipor2
bosterbio.com/bosterbio-gene-info-cards/Adipor2
References
PMID: 12802337 by Yamauchi T., et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.
PMID: 17327425 by Bjursell M., et al. Opposing effects of adiponectin receptors 1 and 2 on energy metabolism.