ADRB3 Antibodies

Beta-3 adrenergic receptor (ADRB3)

Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.

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Gene Information

Human
Gene Name:	ADRB3
Uniprot:	P13945
Entrez:	155

Family

Belongs to:
G-protein coupled receptor 1 family

Alternative Names

ADRB3; ADRB3R; adrenergic, beta-3-, receptor; B3AR; beta-3 Adrenergic R; beta-3 adrenergic receptor; beta3 AdrenergicR; beta-3 AdrenergicR; Beta-3 adrenoceptor; Beta-3 adrenoreceptor; BETA3AR; FLJ99960

Molecular Weight

Mass (kDA):
43.519 kDA

Genomic Context

Human
Location:	8p11.23
Sequence:	8; NC_000008.11 (37962990..37966599, complement)

Tissue Specificity

Expressed mainly in adipose tissues.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

• Obesity
• Insulin Resistance
• Diabetes Mellitus
• Diabetes Mellitus, Non-insulin-dependent
• Hypertensive Disease
• Metabolic Syndrome X
• Cardiovascular Diseases
• Schizophrenia
• Malignant Neoplasms
• Polycystic Ovary Syndrome
• Coronary Heart Disease
• 5,10-methylenetetrahydrofolate Reductase Deficiency

• Heart Diseases
• Hyperinsulinism
• Infarction
• Myocardial Infarction
• Obesity, Abdominal
• Malignant Neoplasm Of Breast
• Mammary Neoplasms

Pathways

• Insulin Secretion
• Pathogenesis
• Secretion
• Energy Homeostasis
• Localization
• Glucose Homeostasis
• Transport
• Lactation
• Electron Transport
• Gallstone Formation
• Eating Behavior
• Menopause
• Response To Drug

• Glomerular Filtration
• Gastric Emptying
• Cytokine Production
• Cell Death
• Response To Olanzapine
• Cell Differentiation
• Lipid Storage

PTMs

• Cleavage

Research Areas

• GPCR
• Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADRB3

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Peer review of Boster Bio: Best Uses Of The ADRB3 Marker

Boster Bio: Best Uses of the ADRB3 marker has been reviewed by Peer Review. It was developed by scientists, and it has been used for research in a variety of disciplines, including forensic science, medicine, and animal health. The authors of this study, Drs. Vatner and Xu, are credited with creating the ADRB3 marker and publishing it for research use.