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- Table of Contents
AHSA1 Antibodies
AND AHSA1 ELISA kits, AHSA1 Proteins
Many biological assays use antibodies to detect AHSA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AHSA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AHSA1 antibodies...
Designing a Western blot for AHSA1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AHSA1 Western Blot GuideAHSA1 Infographic by Boster Bio
All AHSA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05733-2
100 μg/vial
Cat # A05733-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A05739-1
100 µg/vial
Cat # A05739-1
100 µg/vial
AHSA1 Overview
Facts about Activator of 90 kDa heat shock protein ATPase homolog 1.
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1)
Acts as a co-chaperone of HSP90AA1 (PubMed:29127155).
Activates the ATPase activity of HSP90AA1 resulting in increase in its chaperone activity (PubMed:29127155).Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a mutual regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a mutual regulatory mechanism for chaperoning of client proteins (PubMed:29127155).
Gene Information
| Human | |
|---|---|
| Gene Name: | AHSA1 |
| Uniprot: | O95433 |
| Entrez: | 10598 |
Family
| Belongs to: |
|---|
| AHA1 family |
Alternative Names
activator of 90 kDa heat shock protein ATPase homolog 1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast); C14orf3; chromosome 14 open reading frame 3; p38AHA1
Molecular Weight
Mass (kDA):
38.274 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q24.3 |
| Sequence: | 14; NC_000014.9 (77457867..77469472) |
Tissue Specificity
Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
Subcellular Localizations
Cytoplasm, cytosol. Endoplasmic reticulum. May transiently interact with the endoplasmic reticulum.
Diseases
- Cystic Fibrosis
- Fibrosis
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Hereditary Diseases
Interacting Proteins
- GCH1
- HSP90AA1
- HSP90AB1
Pathways
- Transport
- Drug Resistance
- Protein Folding
- Dna Repair
- Mrna Processing
- Cell Growth
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AHSA1
bosterbio.com/bosterbio-gene-info-cards/AHSA1
References
PMID: 11554768 by Sevier C.S., et al. p38: a novel protein that associates with the vesicular stomatitis virus glycoprotein.
PMID: 12504007 by Panaretou B., et al. Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1.