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- Table of Contents
Facts about A-kinase anchor protein 6.
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Human | |
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Gene Name: | AKAP6 |
Uniprot: | Q13023 |
Entrez: | 9472 |
Belongs to: |
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No superfamily |
A kinase (PRKA) anchor protein 6; ADAP6A-kinase anchor protein 6; AKAP100A-kinase anchor protein 100 kDa; AKAP-6; KIAA0311AKAP 100; mAKAPMGC165020; PRKA6ADAP100; protein kinase A anchoring protein 6; Protein kinase A-anchoring protein 6
Mass (kDA):
256.72 kDA
Human | |
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Location: | 14q12 |
Sequence: | 14; NC_000014.9 (32203610..32837684) |
Highly expressed in cardiac and skeletal muscle, followed by brain.
Sarcoplasmic reticulum. Nucleus membrane. In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.
PMID: 10413680 by Kapiloff M.S., et al. mAKAP: an A-kinase anchoring protein targeted to the nuclear membrane of differentiated myocytes.
PMID: 7721854 by McCartney S., et al. Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum.