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- Table of Contents
AKR7A2 Antibodies
AND AKR7A2 ELISA kits, AKR7A2 Proteins
Many biological assays use antibodies to detect AKR7A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with AKR7A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop AKR7A2 antibodies...
Designing a Western blot for AKR7A2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the AKR7A2 Western Blot GuideAKR7A2 Infographic by Boster Bio
All AKR7A2 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A06993-1
100 μg/vial
Cat # A06993-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A06982-2
100 μg/vial
Cat # A06982-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06980-2
100 μg/vial
Cat # A06980-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06975-1
100 μg/vial
Cat # A06975-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06953-1
100 µg/vial
Cat # A06953-1
100 µg/vial
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A06997-1
100 μg/vial
Cat # A06997-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06949-1
100 μg/vial
Cat # A06949-1
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A06972-3
100 µg/vial
Cat # A06972-3
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06967-1
100 μg/vial
Cat # A06967-1
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, WB
$370
Cat # A06984-1
100 μg/vial
Cat # A06984-1
100 μg/vial
Enzyme Activity, SDS-PAGE
$265
Cat # PROTO43488
Starting from 20ug
Cat # PROTO43488
Starting from 20ug
AKR7A2 Overview
Facts about Aflatoxin B1 aldehyde reductase member 2.
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2)
Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in creating the neuromodulator gamma-hydroxybutyrate (GHB).
Has wide substrate specificity. Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro).
Gene Information
| Human | |
|---|---|
| Gene Name: | AKR7A2 |
| Uniprot: | O43488 |
| Entrez: | 8574 |
Family
| Belongs to: |
|---|
| aldo/keto reductase family |
Alternative Names
AFAR1; AFARAFB1-AR1; AFB1 aldehyde reductase 1; AFB1-AR 1; aflatoxin B1 aldehyde reductase member 2; aflatoxin beta1 aldehyde reductase; AKR7; aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase); Aldoketoreductase 7; EC 1.1.1.n11; SSA reductase; Succinic semialdehyde reductase
Molecular Weight
Mass (kDA):
39.589 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.13 |
| Sequence: | 1; NC_000001.11 (19302708..19312146, complement) |
Tissue Specificity
Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed.
Subcellular Localizations
Golgi apparatus. Cytoplasm.
Diseases
- Malignant Neoplasms
- Neurodegenerative Disorders
- Carcinoma
- Neoplasms
- Neuroblastoma
- Endometrial Polyp
- Endometrial Carcinoma
- Astrocytoma
- Liver Diseases
- Adenoma
- Infectious Mononucleosis
- Endometrial Neoplasms
- Aneuploidy
Interacting Proteins
- AKR7A3
- CYGB
Pathways
- Cell Cycle
- Rna Interference
- Localization
- Secretion
- Cell Adhesion
- Transport
- Dna Replication
- Cell Proliferation
PTMs
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/AKR7A2
bosterbio.com/bosterbio-gene-info-cards/AKR7A2
References
PMID: 9576847 by Ireland L.S., et al. Molecular cloning, expression and catalytic activity of a human AKR7 member of the aldo-keto reductase superfamily: evidence that the major 2-carboxybenzaldehyde reductase from human liver is a homologue of rat aflatoxin B1-aldehyde reductase.
PMID: 9823300 by Praml C., et al. Cloning of the human aflatoxin B1-aldehyde reductase gene at 1p35- 1p36.1 in a region frequently altered in human tumor cells.
1 Publications of Boster AKR7A2 Antibodies & ELISA Kits
- PubMed ID: 10.1007/s00774-011-0302-8, The role of α-zearalanol in reversing bone loss induced by ovarian hormone defi...
*More publications can be found for each product on its corresponding product page